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Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine-pyridine-histidine system.
Ali TF, Iwamaru K, Ciftci HI, Koga R, Matsumoto M, Oba Y, Kurosaki H, Fujita M, Okamoto Y, Umezawa K, Nakao M, Hide T, Makino K, Kuratsu J, Abdel-Aziz M, Abuo-Rahma Gel-D, Beshr EA, Otsuka M. Ali TF, et al. Bioorg Med Chem. 2015 Sep 1;23(17):5476-82. doi: 10.1016/j.bmc.2015.07.044. Epub 2015 Jul 29. Bioorg Med Chem. 2015. PMID: 26260338
Design, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothiazole Moiety.
Altıntop MD, Ciftci HI, Radwan MO, Sever B, Kaplancıklı ZA, Ali TFS, Koga R, Fujita M, Otsuka M, Özdemir A. Altıntop MD, et al. Among authors: ali tfs. Molecules. 2017 Dec 27;23(1):59. doi: 10.3390/molecules23010059. Molecules. 2017. PMID: 29280989 Free PMC article.
New SIRT2 inhibitors: Histidine-based bleomycin spin-off.
Ali TFS, Ciftci HI, Radwan MO, Koga R, Ohsugi T, Okiyama Y, Honma T, Nakata A, Ito A, Yoshida M, Fujita M, Otsuka M. Ali TFS, et al. Bioorg Med Chem. 2019 May 1;27(9):1767-1775. doi: 10.1016/j.bmc.2019.03.003. Epub 2019 Mar 2. Bioorg Med Chem. 2019. PMID: 30885568
HSP70 induction by bleomycin metal core analogs.
Ali TFS, Taira N, Iwamaru K, Koga R, Kamo M, Radwan MO, Tateishi H, Kurosaki H, Abdel-Aziz M, Abuo-Rahma GEAA, Beshr EAM, Otsuka M, Fujita M. Ali TFS, et al. Bioorg Med Chem Lett. 2020 Apr 1;30(7):127002. doi: 10.1016/j.bmcl.2020.127002. Epub 2020 Jan 31. Bioorg Med Chem Lett. 2020. PMID: 32044184
33 results