Ali A - Search Results

1

Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance.

Nalam MN, Ali A, Reddy GS, Cao H, Anjum SG, Altman MD, Yilmaz NK, Tidor B, Rana TM, Schiffer CA. Nalam MN, et al. Among authors: ali a. Chem Biol. 2013 Sep 19;20(9):1116-24. doi: 10.1016/j.chembiol.2013.07.014. Epub 2013 Sep 5. Chem Biol. 2013. PMID: 24012370 Free PMC article.

2

Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication.

Hwang S, Tamilarasu N, Kibler K, Cao H, Ali A, Ping YH, Jeang KT, Rana TM. Hwang S, et al. Among authors: ali a. J Biol Chem. 2003 Oct 3;278(40):39092-103. doi: 10.1074/jbc.M301749200. Epub 2003 Jul 11. J Biol Chem. 2003. PMID: 12857725 Free article.

3

Visualizing a correlation between siRNA localization, cellular uptake, and RNAi in living cells.

Chiu YL, Ali A, Chu CY, Cao H, Rana TM. Chiu YL, et al. Among authors: ali a. Chem Biol. 2004 Aug;11(8):1165-75. doi: 10.1016/j.chembiol.2004.06.006. Chem Biol. 2004. PMID: 15324818

4

Dissecting RNA-interference pathway with small molecules.

Chiu YL, Dinesh CU, Chu CY, Ali A, Brown KM, Cao H, Rana TM. Chiu YL, et al. Among authors: ali a. Chem Biol. 2005 Jun;12(6):643-8. doi: 10.1016/j.chembiol.2005.04.016. Chem Biol. 2005. PMID: 15975509

5

Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands.

Ali A, Reddy GS, Cao H, Anjum SG, Nalam MN, Schiffer CA, Rana TM. Ali A, et al. J Med Chem. 2006 Dec 14;49(25):7342-56. doi: 10.1021/jm060666p. J Med Chem. 2006. PMID: 17149864

6

Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis.

Chellappan S, Kiran Kumar Reddy GS, Ali A, Nalam MN, Anjum SG, Cao H, Kairys V, Fernandes MX, Altman MD, Tidor B, Rana TM, Schiffer CA, Gilson MK. Chellappan S, et al. Among authors: ali a. Chem Biol Drug Des. 2007 May;69(5):298-313. doi: 10.1111/j.1747-0285.2007.00514.x. Chem Biol Drug Des. 2007. PMID: 17539822

7

Design and synthesis of HIV-1 protease inhibitors incorporating oxazolidinones as P2/P2' ligands in pseudosymmetric dipeptide isosteres.

Reddy GS, Ali A, Nalam MN, Anjum SG, Cao H, Nathans RS, Schiffer CA, Rana TM. Reddy GS, et al. Among authors: ali a. J Med Chem. 2007 Sep 6;50(18):4316-28. doi: 10.1021/jm070284z. Epub 2007 Aug 16. J Med Chem. 2007. PMID: 17696512 Free PMC article.

8

HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants.

Altman MD, Ali A, Reddy GS, Nalam MN, Anjum SG, Cao H, Chellappan S, Kairys V, Fernandes MX, Gilson MK, Schiffer CA, Rana TM, Tidor B. Altman MD, et al. Among authors: ali a. J Am Chem Soc. 2008 May 14;130(19):6099-113. doi: 10.1021/ja076558p. Epub 2008 Apr 16. J Am Chem Soc. 2008. PMID: 18412349 Free PMC article.

9

Small-molecule inhibition of HIV-1 Vif.

Nathans R, Cao H, Sharova N, Ali A, Sharkey M, Stranska R, Stevenson M, Rana TM. Nathans R, et al. Among authors: ali a. Nat Biotechnol. 2008 Oct;26(10):1187-92. doi: 10.1038/nbt.1496. Epub 2008 Sep 21. Nat Biotechnol. 2008. PMID: 18806783 Free PMC article.

10

Additivity in the analysis and design of HIV protease inhibitors.

Jorissen RN, Reddy GS, Ali A, Altman MD, Chellappan S, Anjum SG, Tidor B, Schiffer CA, Rana TM, Gilson MK. Jorissen RN, et al. Among authors: ali a. J Med Chem. 2009 Feb 12;52(3):737-54. doi: 10.1021/jm8009525. J Med Chem. 2009. PMID: 19193159 Free PMC article.

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