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Exposure to the plasticizer, Di-(2-ethylhexyl) phthalate during juvenile period exacerbates autism-like behavior in adult BTBR T + tf/J mice due to DNA hypomethylation and enhanced inflammation in brain and systemic immune cells.
Nadeem A, Al-Harbi NO, Ahmad SF, Alhazzani K, Attia SM, Alsanea S, Alhoshani A, Mahmood HM, Alfardan AS, Bakheet SA. Nadeem A, et al. Among authors: alhazzani k. Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jul 13;109:110249. doi: 10.1016/j.pnpbp.2021.110249. Epub 2021 Jan 23. Prog Neuropsychopharmacol Biol Psychiatry. 2021. PMID: 33497755
Pharmacological Inhibition of STAT3 by Stattic Ameliorates Clinical Symptoms and Reduces Autoinflammation in Myeloid, Lymphoid, and Neuronal Tissue Compartments in Relapsing-Remitting Model of Experimental Autoimmune Encephalomyelitis in SJL/J Mice.
Alhazzani K, Ahmad SF, Al-Harbi NO, Attia SM, Bakheet SA, Sarawi W, Alqarni SA, Algahtani M, Nadeem A. Alhazzani K, et al. Pharmaceutics. 2021 Jun 22;13(7):925. doi: 10.3390/pharmaceutics13070925. Pharmaceutics. 2021. PMID: 34206429 Free PMC article.
Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies.
Alanazi FE, As Sobeai HM, Alhazzani K, Al-Dhfyan A, Alshammari MA, Alotaibi M, Al-Hosaini K, Korashy HM, Alhoshani A. Alanazi FE, et al. Among authors: alhazzani k. Saudi Pharm J. 2022 Feb;30(2):138-149. doi: 10.1016/j.jsps.2021.12.014. Epub 2021 Dec 31. Saudi Pharm J. 2022. PMID: 35528855 Free PMC article.
Lck signaling inhibition causes improvement in clinical features of psoriatic inflammation through reduction in inflammatory cytokines in CD4+ T cells in imiquimod mouse model.
Al-Harbi NO, Ahmad SF, Almutairi M, Alanazi AZ, Ibrahim KE, Alqarni SA, Alqahtani F, Alhazzani K, Alharbi M, Alasmari F, Nadeem A. Al-Harbi NO, et al. Among authors: alhazzani k. Cell Immunol. 2022 Jun;376:104531. doi: 10.1016/j.cellimm.2022.104531. Epub 2022 May 13. Cell Immunol. 2022. PMID: 35576719
51 results