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Anticancer evaluations of iodoquinazoline substituted with allyl and/or benzyl as dual inhibitors of EGFRWT and EGFRT790M: design, synthesis, ADMET and molecular docking.
Aljohani AKB, El-Adl K, Almohaywi B, Alatawi OM, Alsulaimany M, El-Morsy A, Almadani SA, Alharbi HY, Aljohani MS, Abdulhaleem M FA, Osman HEM, Mohamady S. Aljohani AKB, et al. Among authors: alharbi hy. RSC Adv. 2024 Mar 6;14(12):7964-7980. doi: 10.1039/d4ra00502c. eCollection 2024 Mar 6. RSC Adv. 2024. PMID: 38454937 Free PMC article.
Synthesis, crystal structure, DFT, Hirshfeld surface analysis, energy frameworks and in-Silico drug-targeting PFKFB3 kinase of novel triazolequinoxalin derivative (TZQ) as a therapeutic Strategy against cancer.
Abad N, Al-Ostoot FH, Ashraf S, Chkirate K, Aljohani MS, Alharbi HY, Buhlak S, El Hafi M, Van Meervelt L, Al-Maswari BM, Essassi EM, Ramli Y. Abad N, et al. Among authors: alharbi hy. Heliyon. 2023 Oct 20;9(11):e21312. doi: 10.1016/j.heliyon.2023.e21312. eCollection 2023 Nov. Heliyon. 2023. PMID: 37920528 Free PMC article.
Design, synthesis, docking, ADMET and anticancer evaluations of N-alkyl substituted iodoquinazoline derivatives as dual VEGFR-2 and EGFR inhibitors.
Alsulaimany M, El-Adl K, Aljohani AKB, Alharbi HY, Alatawi OM, Aljohani MS, El-Morsy A, Almadani SA, Alsimaree AA, Salama SA, Keshek DE, Mohamed AA. Alsulaimany M, et al. Among authors: alharbi hy. RSC Adv. 2023 Dec 13;13(51):36301-36321. doi: 10.1039/d3ra07700d. eCollection 2023 Dec 8. RSC Adv. 2023. PMID: 38093733 Free PMC article.
Synthesis, Glucosidase Inhibition, and In Silico Modeling Analysis of Highly Fluorinated 2-Imino-1,3-thiazolines in Search of Potent Antidiabetic Agents.
Zahid LU, Zaib S, Saeed A, Alharbi HY, Aljohani MS, Alharbi O, Rana N, Khan I, Shabir G, Ahmed A, Saleem A, Awwad NS, Ibrahium HA. Zahid LU, et al. Among authors: alharbi hy. ACS Omega. 2024 Mar 20;9(13):15603-15614. doi: 10.1021/acsomega.4c00529. eCollection 2024 Apr 2. ACS Omega. 2024. PMID: 38585118 Free PMC article.
11 results