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Stroma-Mediated Resistance to S63845 and Venetoclax through MCL-1 and BCL-2 Expression Changes Induced by miR-193b-3p and miR-21-5p Dysregulation in Multiple Myeloma.
Cells. 2021 Mar 4;10(3):559. doi: 10.3390/cells10030559.
Cells. 2021.
PMID: 33806619
Free PMC article.
Filanesib for the treatment of multiple myeloma.
Algarín EM, Hernández-García S, Garayoa M, Ocio EM.
Algarín EM, et al.
Expert Opin Investig Drugs. 2020 Jan;29(1):5-14. doi: 10.1080/13543784.2020.1703179. Epub 2019 Dec 12.
Expert Opin Investig Drugs. 2020.
PMID: 31815551
Review.
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Preclinical evaluation of the simultaneous inhibition of MCL-1 and BCL-2 with the combination of S63845 and venetoclax in multiple myeloma.
Algarín EM, Díaz-Tejedor A, Mogollón P, Hernández-García S, Corchete LA, San-Segundo L, Martín-Sánchez M, González-Méndez L, Schoumacher M, Banquet S, Kraus-Berthier L, Kloos I, Derreal A, Halilovic E, Maacke H, Gutiérrez NC, Mateos MV, Paíno T, Garayoa M, Ocio EM.
Algarín EM, et al.
Haematologica. 2020 Mar;105(3):e116-e120. doi: 10.3324/haematol.2018.212308. Epub 2019 Jul 18.
Haematologica. 2020.
PMID: 31320555
Free PMC article.
No abstract available.
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Biological Background of Resistance to Current Standards of Care in Multiple Myeloma.
Mogollón P, Díaz-Tejedor A, Algarín EM, Paíno T, Garayoa M, Ocio EM.
Mogollón P, et al. Among authors: algarin em.
Cells. 2019 Nov 13;8(11):1432. doi: 10.3390/cells8111432.
Cells. 2019.
PMID: 31766279
Free PMC article.
Review.
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The kinesin spindle protein inhibitor filanesib enhances the activity of pomalidomide and dexamethasone in multiple myeloma.
Hernández-García S, San-Segundo L, González-Méndez L, Corchete LA, Misiewicz-Krzeminska I, Martín-Sánchez M, López-Iglesias AA, Algarín EM, Mogollón P, Díaz-Tejedor A, Paíno T, Tunquist B, Mateos MV, Gutiérrez NC, Díaz-Rodriguez E, Garayoa M, Ocio EM.
Hernández-García S, et al. Among authors: algarin em.
Haematologica. 2017 Dec;102(12):2113-2124. doi: 10.3324/haematol.2017.168666. Epub 2017 Aug 31.
Haematologica. 2017.
PMID: 28860344
Free PMC article.
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The Novel Pan-PIM Kinase Inhibitor, PIM447, Displays Dual Antimyeloma and Bone-Protective Effects, and Potently Synergizes with Current Standards of Care.
Paíno T, Garcia-Gomez A, González-Méndez L, San-Segundo L, Hernández-García S, López-Iglesias AA, Algarín EM, Martín-Sánchez M, Corbacho D, Ortiz-de-Solorzano C, Corchete LA, Gutiérrez NC, Maetos MV, Garayoa M, Ocio EM.
Paíno T, et al. Among authors: algarin em.
Clin Cancer Res. 2017 Jan 1;23(1):225-238. doi: 10.1158/1078-0432.CCR-16-0230. Epub 2016 Jul 20.
Clin Cancer Res. 2017.
PMID: 27440267
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Protein Translation Inhibition is Involved in the Activity of the Pan-PIM Kinase Inhibitor PIM447 in Combination with Pomalidomide-Dexamethasone in Multiple Myeloma.
Paíno T, González-Méndez L, San-Segundo L, Corchete LA, Hernández-García S, Díaz-Tejedor A, Algarín EM, Mogollón P, Martín-Sánchez M, Gutiérrez NC, Mateos MV, Garayoa M, Ocio EM.
Paíno T, et al. Among authors: algarin em.
Cancers (Basel). 2020 Sep 24;12(10):2743. doi: 10.3390/cancers12102743.
Cancers (Basel). 2020.
PMID: 32987735
Free PMC article.
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