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Antagonizing FcαR1 (CD89) as treatment in IgA-mediated chronic inflammation and autoimmunity.
Front Immunol. 2023 Apr 4;14:1118539. doi: 10.3389/fimmu.2023.1118539. eCollection 2023.
Front Immunol. 2023.
PMID: 37081893
Free PMC article.
Anti-FcαRI Monoclonal Antibodies Resolve IgA Autoantibody-Mediated Disease.
Bos A, Aleyd E, van der Steen LPE, Winter PJ, Heemskerk N, Pouw SM, Boon L, Musters RJP, Bakema JE, Sitaru C, Cogné M, van Egmond M.
Bos A, et al. Among authors: aleyd e.
Front Immunol. 2022 Mar 15;13:732977. doi: 10.3389/fimmu.2022.732977. eCollection 2022.
Front Immunol. 2022.
PMID: 35371001
Free PMC article.
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IgA enhances NETosis and release of neutrophil extracellular traps by polymorphonuclear cells via Fcα receptor I.
Aleyd E, van Hout MW, Ganzevles SH, Hoeben KA, Everts V, Bakema JE, van Egmond M.
Aleyd E, et al.
J Immunol. 2014 Mar 1;192(5):2374-83. doi: 10.4049/jimmunol.1300261. Epub 2014 Feb 3.
J Immunol. 2014.
PMID: 24493821
Clinical Trial.
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The era of the immunoglobulin A Fc receptor FcαRI; its function and potential as target in disease.
Aleyd E, Heineke MH, van Egmond M.
Aleyd E, et al.
Immunol Rev. 2015 Nov;268(1):123-38. doi: 10.1111/imr.12337.
Immunol Rev. 2015.
PMID: 26497517
Review.
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IgA Complexes in Plasma and Synovial Fluid of Patients with Rheumatoid Arthritis Induce Neutrophil Extracellular Traps via FcαRI.
Aleyd E, Al M, Tuk CW, van der Laken CJ, van Egmond M.
Aleyd E, et al.
J Immunol. 2016 Dec 15;197(12):4552-4559. doi: 10.4049/jimmunol.1502353. Epub 2016 Nov 9.
J Immunol. 2016.
PMID: 27913645
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Rational design of DNA vaccines for the induction of human papillomavirus type 16 E6- and E7-specific cytotoxic T-cell responses.
Oosterhuis K, Aleyd E, Vrijland K, Schumacher TN, Haanen JB.
Oosterhuis K, et al. Among authors: aleyd e.
Hum Gene Ther. 2012 Dec;23(12):1301-12. doi: 10.1089/hum.2012.101. Epub 2012 Oct 31.
Hum Gene Ther. 2012.
PMID: 22971245
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