Alexandre-Moreira MS - Search Results

1

Novel orally active analgesic and anti-inflammatory cyclohexyl-N-acylhydrazone derivatives.

da Silva TF, Bispo Júnior W, Alexandre-Moreira MS, Costa FN, Monteiro CE, Ferreira FF, Barroso RC, Noël F, Sudo RT, Zapata-Sudo G, Lima LM, Barreiro EJ. da Silva TF, et al. Molecules. 2015 Feb 12;20(2):3067-88. doi: 10.3390/molecules20023067. Molecules. 2015. PMID: 25685912 Free PMC article.

2

Antinociceptive profile of (-)-spectaline: a piperidine alkaloid from Cassia leptophylla.

Alexandre-Moreira MS, Viegas C Jr, Palhares de Miranda AL, Bolzani Vda S, Barreiro EJ. Alexandre-Moreira MS, et al. Planta Med. 2003 Sep;69(9):795-9. doi: 10.1055/s-2003-43201. Planta Med. 2003. PMID: 14598202

3

LASSBio-468: a new achiral thalidomide analogue which modulates TNF-alpha and NO production and inhibits endotoxic shock and arthritis in an animal model.

Alexandre-Moreira MS, Takiya CM, de Arruda LB, Pascarelli B, Gomes RN, Castro Faria Neto HC, Lima LM, Barreiro EJ. Alexandre-Moreira MS, et al. Int Immunopharmacol. 2005 Mar;5(3):485-94. doi: 10.1016/j.intimp.2004.10.017. Int Immunopharmacol. 2005. PMID: 15683845

4

Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors.

Duarte CD, Tributino JL, Lacerda DI, Martins MV, Alexandre-Moreira MS, Dutra F, Bechara EJ, De-Paula FS, Goulart MO, Ferreira J, Calixto JB, Nunes MP, Bertho AL, Miranda AL, Barreiro EJ, Fraga CA. Duarte CD, et al. Bioorg Med Chem. 2007 Mar 15;15(6):2421-33. doi: 10.1016/j.bmc.2007.01.013. Epub 2007 Jan 17. Bioorg Med Chem. 2007. PMID: 17275312

5

Antinociceptive profile of 2,3,6-trisubstituted piperidine alkaloids: 3-O-acetyl-spectaline and semi-synthetic derivatives of (-)-spectaline.

Viegas C Jr, Alexandre-Moreira MS, Fraga CA, Barreiro EJ, Bolzani Vda S, de Miranda AL. Viegas C Jr, et al. Chem Pharm Bull (Tokyo). 2008 Apr;56(4):407-12. doi: 10.1248/cpb.56.407. Chem Pharm Bull (Tokyo). 2008. PMID: 18379082 Free article.

6

Synthesis and pharmacological evaluation of N-phenyl-acetamide sulfonamides designed as novel non-hepatotoxic analgesic candidates.

Barbosa ML, Melo GM, da Silva YK, Lopes Rde O, de Souza ET, de Queiroz AC, Smaniotto S, Alexandre-Moreira MS, Barreiro EJ, Lima LM. Barbosa ML, et al. Eur J Med Chem. 2009 Sep;44(9):3612-20. doi: 10.1016/j.ejmech.2009.02.026. Epub 2009 Mar 4. Eur J Med Chem. 2009. PMID: 19327871

7

Synthesis and pharmacological evaluation of pyrazine N-acylhydrazone derivatives designed as novel analgesic and anti-inflammatory drug candidates.

da Silva YK, Augusto CV, de Castro Barbosa ML, de Albuquerque Melo GM, de Queiroz AC, de Lima Matos Freire Dias T, Júnior WB, Barreiro EJ, Lima LM, Alexandre-Moreira MS. da Silva YK, et al. Bioorg Med Chem. 2010 Jul 15;18(14):5007-15. doi: 10.1016/j.bmc.2010.06.002. Epub 2010 Jun 8. Bioorg Med Chem. 2010. PMID: 20598893

8

Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms.

dos Santos JL, Lanaro C, Lima LM, Gambero S, Franco-Penteado CF, Alexandre-Moreira MS, Wade M, Yerigenahally S, Kutlar A, Meiler SE, Costa FF, Chung M. dos Santos JL, et al. J Med Chem. 2011 Aug 25;54(16):5811-9. doi: 10.1021/jm200531f. Epub 2011 Jul 25. J Med Chem. 2011. PMID: 21766854

9

Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (H(2)LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H(2)LASSBio-1064) and their zinc(II) complexes.

Júnior WB, Alexandre-Moreira MS, Alves MA, Perez-Rebolledo A, Parrilha GL, Castellano EE, Piro OE, Barreiro EJ, Lima LM, Beraldo H. Júnior WB, et al. Molecules. 2011 Aug 15;16(8):6902-15. doi: 10.3390/molecules16086902. Molecules. 2011. PMID: 21844840 Free PMC article.

10

Design, synthesis, antinociceptive and anti-inflammatory activities of novel piroxicam analogues.

de Miranda AS, Bispo Júnior W, da Silva YK, Alexandre-Moreira MS, Castro Rde P, Sabino JR, Lião LM, Lima LM, Barreiro EJ. de Miranda AS, et al. Molecules. 2012 Nov 28;17(12):14126-45. doi: 10.3390/molecules171214126. Molecules. 2012. PMID: 23192189 Free PMC article.

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