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Transcriptomic analysis of HEK293A cells with a CRISPR/Cas9-mediated TDP1 knockout.
Dyrkheeva NS, Zakharenko AL, Malakhova AA, Okorokova LS, Shtokalo DN, Medvedev SP, Tupikin AA, Kabilov MR, Lavrik OI. Dyrkheeva NS, et al. Among authors: zakharenko al. Biochim Biophys Acta Gen Subj. 2024 Apr 14;1868(7):130616. doi: 10.1016/j.bbagen.2024.130616. Online ahead of print. Biochim Biophys Acta Gen Subj. 2024. PMID: 38621596
Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice with Lewis Carcinoma by Tdp1 Inhibitors-New Usnic Acid Derivatives.
Kornienko TE, Chepanova AA, Zakharenko AL, Filimonov AS, Luzina OA, Dyrkheeva NS, Nikolin VP, Popova NA, Salakhutdinov NF, Lavrik OI. Kornienko TE, et al. Among authors: zakharenko al. Int J Mol Sci. 2024 Jan 19;25(2):1210. doi: 10.3390/ijms25021210. Int J Mol Sci. 2024. PMID: 38279210 Free PMC article.
Pharmacokinetic study of Tdp1 inhibitor resulted in a significant increase in antitumor effect in the treatment of Lewis lung carcinoma in mice by its combination with topotecan.
Okhina AA, Kornienko TE, Rogachev AD, Luzina OA, Popova NA, Nikolin VP, Zakharenko AL, Dyrkheeva NS, Pokrovsky AG, Salakhutdinov NF, Lavrik OI. Okhina AA, et al. Among authors: zakharenko al. J Pharm Biomed Anal. 2023 Nov 30;236:115731. doi: 10.1016/j.jpba.2023.115731. Epub 2023 Sep 18. J Pharm Biomed Anal. 2023. PMID: 37741072
Adamantane-Monoterpenoid Conjugates Linked via Heterocyclic Linkers Enhance the Cytotoxic Effect of Topotecan.
Munkuev AA, Dyrkheeva NS, Kornienko TE, Ilina ES, Ivankin DI, Suslov EV, Korchagina DV, Gatilov YV, Zakharenko AL, Malakhova AA, Reynisson J, Volcho KP, Salakhutdinov NF, Lavrik OI. Munkuev AA, et al. Among authors: zakharenko al. Molecules. 2022 May 24;27(11):3374. doi: 10.3390/molecules27113374. Molecules. 2022. PMID: 35684313 Free PMC article.
31 results