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Author Correction: CIS is a potent checkpoint in NK cell-mediated tumor immunity.
Delconte RB, Kolesnik TB, Dagley LF, Rautela J, Shi W, Putz EM, Stannard K, Zhang JG, Teh C, Firth M, Ushiki T, Andoniou CE, Degli-Esposti MA, Sharp PP, Sanvitale CE, Infusini G, Liau NPD, Linossi EM, Burns CJ, Carotta S, Gray DHD, Seillet C, Hutchinson DS, Belz GT, Webb AI, Alexander WS, Li SS, Bullock AN, Babon JJ, Smyth MJ, Nicholson SE, Huntington ND. Delconte RB, et al. Among authors: alexander ws. Nat Immunol. 2024 Feb;25(2):371-372. doi: 10.1038/s41590-023-01714-8. Nat Immunol. 2024. PMID: 38087084 No abstract available.
Twenty proteins containing a C-terminal SOCS box form five structural classes.
Hilton DJ, Richardson RT, Alexander WS, Viney EM, Willson TA, Sprigg NS, Starr R, Nicholson SE, Metcalf D, Nicola NA. Hilton DJ, et al. Among authors: alexander ws. Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):114-9. doi: 10.1073/pnas.95.1.114. Proc Natl Acad Sci U S A. 1998. PMID: 9419338 Free PMC article.
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation.
Zhang JG, Farley A, Nicholson SE, Willson TA, Zugaro LM, Simpson RJ, Moritz RL, Cary D, Richardson R, Hausmann G, Kile BT, Kent SB, Alexander WS, Metcalf D, Hilton DJ, Nicola NA, Baca M. Zhang JG, et al. Among authors: alexander ws. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2071-6. doi: 10.1073/pnas.96.5.2071. Proc Natl Acad Sci U S A. 1999. PMID: 10051596 Free PMC article.
Negative regulation of cytokine signaling by the SOCS proteins.
Nicola NA, Nicholson SE, Metcalf D, Zhang JG, Baca M, Farley A, Willson TA, Starr R, Alexander W, Hilton DJ. Nicola NA, et al. Cold Spring Harb Symp Quant Biol. 1999;64:397-404. doi: 10.1101/sqb.1999.64.397. Cold Spring Harb Symp Quant Biol. 1999. PMID: 11232314 Review. No abstract available.
SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.
Krebs DL, Uren RT, Metcalf D, Rakar S, Zhang JG, Starr R, De Souza DP, Hanzinikolas K, Eyles J, Connolly LM, Simpson RJ, Nicola NA, Nicholson SE, Baca M, Hilton DJ, Alexander WS. Krebs DL, et al. Among authors: alexander ws. Mol Cell Biol. 2002 Jul;22(13):4567-78. doi: 10.1128/MCB.22.13.4567-4578.2002. Mol Cell Biol. 2002. PMID: 12052866 Free PMC article.
SOCS3 negatively regulates IL-6 signaling in vivo.
Croker BA, Krebs DL, Zhang JG, Wormald S, Willson TA, Stanley EG, Robb L, Greenhalgh CJ, Förster I, Clausen BE, Nicola NA, Metcalf D, Hilton DJ, Roberts AW, Alexander WS. Croker BA, et al. Among authors: alexander ws. Nat Immunol. 2003 Jun;4(6):540-5. doi: 10.1038/ni931. Epub 2003 May 18. Nat Immunol. 2003. PMID: 12754505
Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling.
Nicholson SE, Metcalf D, Sprigg NS, Columbus R, Walker F, Silva A, Cary D, Willson TA, Zhang JG, Hilton DJ, Alexander WS, Nicola NA. Nicholson SE, et al. Among authors: alexander ws. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2328-33. doi: 10.1073/pnas.0409675102. Epub 2005 Feb 3. Proc Natl Acad Sci U S A. 2005. PMID: 15695332 Free PMC article.
260 results