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Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance.
Deng Y, Diepstraten ST, Potts MA, Giner G, Trezise S, Ng AP, Healey G, Kane SR, Cooray A, Behrens K, Heidersbach A, Kueh AJ, Pal M, Wilcox S, Tai L, Alexander WS, Visvader JE, Nutt SL, Strasser A, Haley B, Zhao Q, Kelly GL, Herold MJ. Deng Y, et al. Among authors: alexander ws. Nat Commun. 2022 Aug 12;13(1):4739. doi: 10.1038/s41467-022-32485-9. Nat Commun. 2022. PMID: 35961968 Free PMC article.
The transgenic window on lymphoid malignancy.
Adams JM, Harris AW, Vaux DL, Alexander WS, Rosenbaum H, Klinken SP, Strasser A, Bath ML, McNeall J, Cory S. Adams JM, et al. Among authors: alexander ws. Princess Takamatsu Symp. 1989;20:297-309. Princess Takamatsu Symp. 1989. PMID: 2518688
c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3.
Sutherland KD, Vaillant F, Alexander WS, Wintermantel TM, Forrest NC, Holroyd SL, McManus EJ, Schutz G, Watson CJ, Chodosh LA, Lindeman GJ, Visvader JE. Sutherland KD, et al. Among authors: alexander ws. EMBO J. 2006 Dec 13;25(24):5805-15. doi: 10.1038/sj.emboj.7601455. Epub 2006 Nov 30. EMBO J. 2006. PMID: 17139252 Free PMC article.
Agm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development.
Greig KT, Antonchuk J, Metcalf D, Morgan PO, Krebs DL, Zhang JG, Hacking DF, Bode L, Robb L, Kranz C, de Graaf C, Bahlo M, Nicola NA, Nutt SL, Freeze HH, Alexander WS, Hilton DJ, Kile BT. Greig KT, et al. Among authors: alexander ws. Mol Cell Biol. 2007 Aug;27(16):5849-59. doi: 10.1128/MCB.00802-07. Epub 2007 Jun 4. Mol Cell Biol. 2007. PMID: 17548465 Free PMC article.
Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia.
Tang JZ, Carmichael CL, Shi W, Metcalf D, Ng AP, Hyland CD, Jenkins NA, Copeland NG, Howell VM, Zhao ZJ, Smyth GK, Kile BT, Alexander WS. Tang JZ, et al. Among authors: alexander ws. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6091-6. doi: 10.1073/pnas.1304234110. Epub 2013 Mar 26. Proc Natl Acad Sci U S A. 2013. PMID: 23533276 Free PMC article.
260 results