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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism.
Murphy JM, Czabotar PE, Hildebrand JM, Lucet IS, Zhang JG, Alvarez-Diaz S, Lewis R, Lalaoui N, Metcalf D, Webb AI, Young SN, Varghese LN, Tannahill GM, Hatchell EC, Majewski IJ, Okamoto T, Dobson RC, Hilton DJ, Babon JJ, Nicola NA, Strasser A, Silke J, Alexander WS. Murphy JM, et al. Among authors: alexander ws. Immunity. 2013 Sep 19;39(3):443-53. doi: 10.1016/j.immuni.2013.06.018. Epub 2013 Sep 5. Immunity. 2013. PMID: 24012422 Free article.
Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned Il-13 receptor and Il-4 receptor alpha-chains.
Zhang JG, Hilton DJ, Willson TA, McFarlane C, Roberts BA, Moritz RL, Simpson RJ, Alexander WS, Metcalf D, Nicola NA. Zhang JG, et al. Among authors: alexander ws. J Biol Chem. 1997 Apr 4;272(14):9474-80. doi: 10.1074/jbc.272.14.9474. J Biol Chem. 1997. PMID: 9083087 Free article.
A family of cytokine-inducible inhibitors of signalling.
Starr R, Willson TA, Viney EM, Murray LJ, Rayner JR, Jenkins BJ, Gonda TJ, Alexander WS, Metcalf D, Nicola NA, Hilton DJ. Starr R, et al. Among authors: alexander ws. Nature. 1997 Jun 26;387(6636):917-21. doi: 10.1038/43206. Nature. 1997. PMID: 9202125
Twenty proteins containing a C-terminal SOCS box form five structural classes.
Hilton DJ, Richardson RT, Alexander WS, Viney EM, Willson TA, Sprigg NS, Starr R, Nicholson SE, Metcalf D, Nicola NA. Hilton DJ, et al. Among authors: alexander ws. Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):114-9. doi: 10.1073/pnas.95.1.114. Proc Natl Acad Sci U S A. 1998. PMID: 9419338 Free PMC article.
260 results