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Clinical and analytical validation of FoundationOne Liquid CDx, a novel 324-Gene cfDNA-based comprehensive genomic profiling assay for cancers of solid tumor origin.
Woodhouse R, Li M, Hughes J, Delfosse D, Skoletsky J, Ma P, Meng W, Dewal N, Milbury C, Clark T, Donahue A, Stover D, Kennedy M, Dacpano-Komansky J, Burns C, Vietz C, Alexander B, Hegde P, Dennis L. Woodhouse R, et al. Among authors: alexander b. PLoS One. 2020 Sep 25;15(9):e0237802. doi: 10.1371/journal.pone.0237802. eCollection 2020. PLoS One. 2020. PMID: 32976510 Free PMC article.
Evidence-Based Development and Clinical Use of Precision Oncology Therapeutics.
Comment LA, Ward AF, Schrock AB, Fabrizio D, Venstrom JM, Hegde PS, Alexander BM. Comment LA, et al. Among authors: alexander bm. Clin Pharmacol Ther. 2020 Sep;108(3):440-443. doi: 10.1002/cpt.1967. Epub 2020 Aug 3. Clin Pharmacol Ther. 2020. PMID: 32744335 Free PMC article. No abstract available.
Somatic HLA Class I Loss Is a Widespread Mechanism of Immune Evasion Which Refines the Use of Tumor Mutational Burden as a Biomarker of Checkpoint Inhibitor Response.
Montesion M, Murugesan K, Jin DX, Sharaf R, Sanchez N, Guria A, Minker M, Li G, Fisher V, Sokol ES, Pavlick DC, Moore JA, Braly A, Singal G, Fabrizio D, Comment LA, Rizvi NA, Alexander BM, Frampton GM, Hegde PS, Albacker LA. Montesion M, et al. Cancer Discov. 2021 Feb;11(2):282-292. doi: 10.1158/2159-8290.CD-20-0672. Epub 2020 Oct 30. Cancer Discov. 2021. PMID: 33127846
Genomic Analysis of Circulating Tumor DNA in 3,334 Patients with Advanced Prostate Cancer Identifies Targetable BRCA Alterations and AR Resistance Mechanisms.
Tukachinsky H, Madison RW, Chung JH, Gjoerup OV, Severson EA, Dennis L, Fendler BJ, Morley S, Zhong L, Graf RP, Ross JS, Alexander BM, Abida W, Chowdhury S, Ryan CJ, Fizazi K, Golsorkhi T, Watkins SP, Simmons A, Loehr A, Venstrom JM, Oxnard GR. Tukachinsky H, et al. Clin Cancer Res. 2021 Jun 1;27(11):3094-3105. doi: 10.1158/1078-0432.CCR-20-4805. Epub 2021 Feb 8. Clin Cancer Res. 2021. PMID: 33558422 Free PMC article.
Comprehensive genomic profiling of histologic subtypes of urethral carcinomas.
Jacob J, Necchi A, Grivas P, Hughes M, Sanford T, Mollapour M, Shapiro O, Talal A, Sokol E, Vergilio JA, Killian J, Lin D, Williams E, Tse J, Ramkissoon S, Severson E, Hemmerich A, Ferguson N, Edgerly C, Duncan D, Huang R, Chung J, Madison R, Alexander B, Venstrom J, Reddy P, McGregor K, Elvin J, Schrock A, Danziger N, Pavlick D, Ross J, Bratslavsky G. Jacob J, et al. Among authors: alexander b. Urol Oncol. 2021 Oct;39(10):731.e1-731.e15. doi: 10.1016/j.urolonc.2020.12.021. Epub 2021 Jun 30. Urol Oncol. 2021. PMID: 34215504
Retrospective analysis of real-world data to determine clinical outcomes of patients with advanced non-small cell lung cancer following cell-free circulating tumor DNA genomic profiling.
Madison R, Schrock AB, Castellanos E, Gregg JP, Snider J, Ali SM, Miller VA, Singal G, Alexander BM, Venstrom JM, Chung JH. Madison R, et al. Among authors: alexander bm. Lung Cancer. 2020 Oct;148:69-78. doi: 10.1016/j.lungcan.2020.07.033. Epub 2020 Aug 6. Lung Cancer. 2020. PMID: 32823229 Free article.
A pan-cancer analysis of PD-L1 immunohistochemistry and gene amplification, tumor mutation burden and microsatellite instability in 48,782 cases.
Huang RSP, Haberberger J, Severson E, Duncan DL, Hemmerich A, Edgerly C, Ferguson NL, Williams E, Elvin J, Vergilio JA, Killian JK, Lin DI, Tse J, Hiemenz M, Owens C, Danziger N, Hegde PS, Venstrom J, Alexander B, Ross JS, Ramkissoon SH. Huang RSP, et al. Among authors: alexander b. Mod Pathol. 2021 Feb;34(2):252-263. doi: 10.1038/s41379-020-00664-y. Epub 2020 Sep 3. Mod Pathol. 2021. PMID: 32884129 Free article.
Genomic Profiling of Circulating Tumor DNA From Cerebrospinal Fluid to Guide Clinical Decision Making for Patients With Primary and Metastatic Brain Tumors.
Ramkissoon LA, Pegram W, Haberberger J, Danziger N, Lesser G, Strowd R, Dahiya S, Cummings TJ, Bi WL, Abedalthagafi M, Sathyan P, McGregor K, Reddy P, Severson E, Williams E, Lin D, Edgerly C, Huang RSP, Hemmerich A, Creeden J, Brown C, Venstrom J, Hegde P, Ross JS, Alexander BM, Elvin J, Ramkissoon SH. Ramkissoon LA, et al. Front Neurol. 2020 Oct 19;11:544680. doi: 10.3389/fneur.2020.544680. eCollection 2020. Front Neurol. 2020. PMID: 33192972 Free PMC article. Review.
1,755 results