Alex Straiker - Search Results

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Results by year

Year	Number of Results
2002	1
2003	1
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CB1 Receptor Negative Allosteric Modulators as a Potential Tool to Reverse Cannabinoid Toxicity.

Flavin A, Azizi P, Murataeva N, Yust K, Du W, Ross R, Greig I, Nguyen T, Zhang Y, Mackie K, Straiker A. Flavin A, et al. Among authors: straiker a. Molecules. 2024 Apr 20;29(8):1881. doi: 10.3390/molecules29081881. Molecules. 2024. PMID: 38675703 Free PMC article.

Structure-Activity Relationship Study of Cannabidiol-Based Analogs as Negative Allosteric Modulators of the μ-Opioid Receptor.

Bosquez-Berger T, Gudorf JA, Kuntz CP, Desmond JA, Schlebach JP, VanNieuwenhze MS, Straiker A. Bosquez-Berger T, et al. Among authors: straiker a. J Med Chem. 2023 Jul 27;66(14):9466-9494. doi: 10.1021/acs.jmedchem.3c00061. Epub 2023 Jul 12. J Med Chem. 2023. PMID: 37437224

A collection of cannabinoid-related negative findings from autaptic hippocampal neurons.

Straiker A, Dvorakova M, Bosquez-Berger T, Blahos J, Mackie K. Straiker A, et al. Sci Rep. 2023 Jun 13;13(1):9610. doi: 10.1038/s41598-023-36710-3. Sci Rep. 2023. PMID: 37311900 Free PMC article.

Differential Enantiomer-Specific Signaling of Cannabidiol at CB₁ Receptors.

Bosquez-Berger T, Wilson S, Iliopoulos-Tsoutsouvas C, Jiang S, Wager-Miller J, Nikas SP, Mackie KP, Makriyannis A, Straiker A. Bosquez-Berger T, et al. Among authors: straiker a. Mol Pharmacol. 2022 Dec;102(6):259-268. doi: 10.1124/molpharm.121.000305. Epub 2022 Sep 24. Mol Pharmacol. 2022. PMID: 36153039 Free PMC article.

A Critical Evaluation of Terpenoid Signaling at Cannabinoid CB1 Receptors in a Neuronal Model.

Dvorakova M, Wilson S, Corey W, Billingsley J, Zimmowitch A, Tracey J, Straiker A, Mackie K. Dvorakova M, et al. Among authors: straiker a. Molecules. 2022 Sep 2;27(17):5655. doi: 10.3390/molecules27175655. Molecules. 2022. PMID: 36080421 Free PMC article.

Cannabinoid CB1 receptors regulate salivation.

Andreis K, Billingsley J, Naimi Shirazi K, Wager-Miller J, Johnson C, Bradshaw H, Straiker A. Andreis K, et al. Among authors: straiker a. Sci Rep. 2022 Aug 19;12(1):14182. doi: 10.1038/s41598-022-17987-2. Sci Rep. 2022. PMID: 35986066 Free PMC article.

Design, synthesis, and pharmacological profiling of cannabinoid 1 receptor allosteric modulators: Preclinical efficacy of C2-group GAT211 congeners for reducing intraocular pressure.

Garai S, Schaffer PC, Laprairie RB, Janero DR, Pertwee RG, Straiker A, Thakur GA. Garai S, et al. Among authors: straiker a. Bioorg Med Chem. 2021 Nov 15;50:116421. doi: 10.1016/j.bmc.2021.116421. Epub 2021 Sep 25. Bioorg Med Chem. 2021. PMID: 34634617

An Evaluation of Understudied Phytocannabinoids and Their Effects in Two Neuronal Models.

Straiker A, Wilson S, Corey W, Dvorakova M, Bosquez T, Tracey J, Wilkowski C, Ho K, Wager-Miller J, Mackie K. Straiker A, et al. Molecules. 2021 Sep 2;26(17):5352. doi: 10.3390/molecules26175352. Molecules. 2021. PMID: 34500785 Free PMC article.

Cannabinoids Regulate Sensory Processing in Early Olfactory and Visual Neural Circuits.

Heinbockel T, Straiker A. Heinbockel T, et al. Among authors: straiker a. Front Neural Circuits. 2021 Jul 7;15:662349. doi: 10.3389/fncir.2021.662349. eCollection 2021. Front Neural Circuits. 2021. PMID: 34305536 Free PMC article. Review.

Discovery of a Biased Allosteric Modulator for Cannabinoid 1 Receptor: Preclinical Anti-Glaucoma Efficacy.

Garai S, Leo LM, Szczesniak AM, Hurst DP, Schaffer PC, Zagzoog A, Black T, Deschamps JR, Miess E, Schulz S, Janero DR, Straiker A, Pertwee RG, Abood ME, Kelly MEM, Reggio PH, Laprairie RB, Thakur GA. Garai S, et al. Among authors: straiker a. J Med Chem. 2021 Jun 24;64(12):8104-8126. doi: 10.1021/acs.jmedchem.1c00040. Epub 2021 Apr 7. J Med Chem. 2021. PMID: 33826336

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