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RUNX1 isoform disequilibrium promotes the development of trisomy 21-associated myeloid leukemia.
Gialesaki S, Bräuer-Hartmann D, Issa H, Bhayadia R, Alejo-Valle O, Verboon L, Schmell AL, Laszig S, Regényi E, Schuschel K, Labuhn M, Ng M, Winkler R, Ihling C, Sinz A, Glaß M, Hüttelmaier S, Matzk S, Schmid L, Strüwe FJ, Kadel SK, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH. Gialesaki S, et al. Among authors: alejo valle o. Blood. 2023 Mar 9;141(10):1105-1118. doi: 10.1182/blood.2022017619. Blood. 2023. PMID: 36493345 Free PMC article.
The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis.
Alejo-Valle O, Weigert K, Bhayadia R, Ng M, Issa H, Beyer C, Emmrich S, Schuschel K, Ihling C, Sinz A, Zimmermann M, Wickenhauser C, Flasinski M, Regenyi E, Labuhn M, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH. Alejo-Valle O, et al. Blood. 2022 Feb 3;139(5):651-665. doi: 10.1182/blood.2021012231. Blood. 2022. PMID: 34570885 Free PMC article.
Chromosome 21 gain is dispensable for transient myeloproliferative disorder driven by a novel GATA1 mutation.
Lukes J Jr, Danek P, Alejo-Valle O, Potuckova E, Gahura O, Heckl D, Starkova J, Stary J, Mejstrikova E, Alberich-Jorda M, Zuna J, Trka J, Klusmann JH, Zaliova M. Lukes J Jr, et al. Among authors: alejo valle o. Leukemia. 2020 Sep;34(9):2503-2508. doi: 10.1038/s41375-020-0769-1. Epub 2020 Feb 24. Leukemia. 2020. PMID: 32094462 No abstract available.
Direct Conversion of Fibroblasts to Megakaryocyte Progenitors.
Pulecio J, Alejo-Valle O, Capellera-Garcia S, Vitaloni M, Rio P, Mejía-Ramírez E, Caserta I, Bueren JA, Flygare J, Raya A. Pulecio J, et al. Among authors: alejo valle o. Cell Rep. 2016 Oct 11;17(3):671-683. doi: 10.1016/j.celrep.2016.09.036. Cell Rep. 2016. PMID: 27732845 Free article.