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SEVA 4.0: an update of the Standard European Vector Architecture database for advanced analysis and programming of bacterial phenotypes.
Martínez-García E, Fraile S, Algar E, Aparicio T, Velázquez E, Calles B, Tas H, Blázquez B, Martín B, Prieto C, Sánchez-Sampedro L, Nørholm MHH, Volke DC, Wirth NT, Dvořák P, Alejaldre L, Grozinger L, Crowther M, Goñi-Moreno A, Nikel PI, Nogales J, de Lorenzo V. Martínez-García E, et al. Among authors: alejaldre l. Nucleic Acids Res. 2023 Jan 6;51(D1):D1558-D1567. doi: 10.1093/nar/gkac1059. Nucleic Acids Res. 2023. PMID: 36420904 Free PMC article.
A conserved SH3-like fold in diverse putative proteins tetramerizes into an oxidoreductase providing an antimicrobial resistance phenotype.
Lemay-St-Denis C, Alejaldre L, Jemouai Z, Lafontaine K, St-Aubin M, Hitache K, Valikhani D, Weerasinghe NW, Létourneau M, Thibodeaux CJ, Doucet N, Baron C, Copp JN, Pelletier JN. Lemay-St-Denis C, et al. Among authors: alejaldre l. Philos Trans R Soc Lond B Biol Sci. 2023 Feb 27;378(1871):20220040. doi: 10.1098/rstb.2022.0040. Epub 2023 Jan 11. Philos Trans R Soc Lond B Biol Sci. 2023. PMID: 36633286 Free PMC article.
Tuning Selectivity in CalA Lipase: Beyond Tunnel Engineering.
Alejaldre L, Lemay-St-Denis C, Pelletier JN, Quaglia D. Alejaldre L, et al. Biochemistry. 2023 Jan 17;62(2):396-409. doi: 10.1021/acs.biochem.2c00513. Epub 2022 Dec 29. Biochemistry. 2023. PMID: 36580299 Free PMC article.
Development of sulfahydantoin derivatives as β-lactamase inhibitors.
Paquet-Côté PA, Alejaldre L, Lapointe Verreault C, Gobeil SMC, Lamoureux R, Bédard L, Normandeau CO, Lemay-St-Denis C, Pelletier JN, Voyer N. Paquet-Côté PA, et al. Among authors: alejaldre l. Bioorg Med Chem Lett. 2021 Mar 1;35:127781. doi: 10.1016/j.bmcl.2021.127781. Epub 2021 Jan 8. Bioorg Med Chem Lett. 2021. PMID: 33422604
Integron-Associated DfrB4, a Previously Uncharacterized Member of the Trimethoprim-Resistant Dihydrofolate Reductase B Family, Is a Clinically Identified Emergent Source of Antibiotic Resistance.
Toulouse JL, Edens TJ, Alejaldre L, Manges AR, Pelletier JN. Toulouse JL, et al. Among authors: alejaldre l. Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02665-16. doi: 10.1128/AAC.02665-16. Print 2017 May. Antimicrob Agents Chemother. 2017. PMID: 28242670 Free PMC article.
12 results