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Non-replicating Mycobacterium tuberculosis elicits a reduced infectivity profile with corresponding modifications to the cell wall and extracellular matrix.
Bacon J, Alderwick LJ, Allnutt JA, Gabasova E, Watson R, Hatch KA, Clark SO, Jeeves RE, Marriott A, Rayner E, Tolley H, Pearson G, Hall G, Besra GS, Wernisch L, Williams A, Marsh PD. Bacon J, et al. Among authors: alderwick lj. PLoS One. 2014 Feb 6;9(2):e87329. doi: 10.1371/journal.pone.0087329. eCollection 2014. PLoS One. 2014. PMID: 24516549 Free PMC article.
Azetidines Kill Multidrug-Resistant Mycobacterium tuberculosis without Detectable Resistance by Blocking Mycolate Assembly.
Cui Y, Lanne A, Peng X, Browne E, Bhatt A, Coltman NJ, Craven P, Cox LR, Cundy NJ, Dale K, Feula A, Frampton J, Fung M, Morton M, Goff A, Salih M, Lang X, Li X, Moon C, Pascoe J, Portman V, Press C, Schulz-Utermoehl T, Lee S, Tortorella MD, Tu Z, Underwood ZE, Wang C, Yoshizawa A, Zhang T, Waddell SJ, Bacon J, Alderwick L, Fossey JS, Neagoie C. Cui Y, et al. J Med Chem. 2024 Feb 22;67(4):2529-2548. doi: 10.1021/acs.jmedchem.3c01643. Epub 2024 Feb 8. J Med Chem. 2024. PMID: 38331432 Free PMC article.
Regulation of cell wall synthesis and growth.
Dover LG, Alderwick LJ, Brown AK, Futterer K, Besra GS. Dover LG, et al. Among authors: alderwick lj. Curr Mol Med. 2007 May;7(3):247-76. doi: 10.2174/156652407780598601. Curr Mol Med. 2007. PMID: 17504111 Review.
Tuberculosis: a balanced diet of lipids and carbohydrates.
Bhowruth V, Alderwick LJ, Brown AK, Bhatt A, Besra GS. Bhowruth V, et al. Among authors: alderwick lj. Biochem Soc Trans. 2008 Aug;36(Pt 4):555-65. doi: 10.1042/BST0360555. Biochem Soc Trans. 2008. PMID: 18631118 Review.
The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the α(1 → 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis.
Jankute M, Alderwick LJ, Moorey AR, Joe M, Gurcha SS, Eggeling L, Lowary TL, Dell A, Pang PC, Yang T, Haslam S, Besra GS. Jankute M, et al. Among authors: alderwick lj. Cell Surf. 2018 Jun;2:38-53. doi: 10.1016/j.tcsw.2018.06.003. Cell Surf. 2018. PMID: 30046665 Free PMC article.
53 results