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mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.
Garros-Regulez L, Aldaz P, Arrizabalaga O, Moncho-Amor V, Carrasco-Garcia E, Manterola L, Moreno-Cugnon L, Barrena C, Villanua J, Ruiz I, Pollard S, Lovell-Badge R, Sampron N, Garcia I, Matheu A. Garros-Regulez L, et al. Among authors: aldaz p. Expert Opin Ther Targets. 2016;20(4):393-405. doi: 10.1517/14728222.2016.1151002. Expert Opin Ther Targets. 2016. PMID: 26878385 Free PMC article.
Therapeutic strategies targeting glioblastoma stem cells.
Carrasco-Garcia E, Sampron N, Aldaz P, Arrizabalaga O, Villanua J, Barrena C, Ruiz I, Arrazola M, Lawrie C, Matheu A. Carrasco-Garcia E, et al. Among authors: aldaz p. Recent Pat Anticancer Drug Discov. 2013 Sep;8(3):216-27. doi: 10.2174/15748928113089990002. Recent Pat Anticancer Drug Discov. 2013. PMID: 23607282 Review.
Indirect costs associated with glioblastoma: Experience at one hospital.
Undabeitia J, Torres-Bayona S, Samprón N, Arrázola M, Bollar A, Armendariz M, Torres P, Ruiz I, Caballero MC, Egaña L, Querejeta A, Villanua J, Pardo E, Etxegoien I, Liceaga G, Urtasun M, Michan M, Emparanza JI, Aldaz P, Matheu A, Úrculo E. Undabeitia J, et al. Among authors: aldaz p. Neurologia (Engl Ed). 2018 Mar;33(2):85-91. doi: 10.1016/j.nrl.2016.05.003. Epub 2016 Jul 20. Neurologia (Engl Ed). 2018. PMID: 27449154 Free article. English, Spanish.
Stratification and therapeutic potential of PML in metastatic breast cancer.
Martín-Martín N, Piva M, Urosevic J, Aldaz P, Sutherland JD, Fernández-Ruiz S, Arreal L, Torrano V, Cortazar AR, Planet E, Guiu M, Radosevic-Robin N, Garcia S, Macías I, Salvador F, Domenici G, Rueda OM, Zabala-Letona A, Arruabarrena-Aristorena A, Zúñiga-García P, Caro-Maldonado A, Valcárcel-Jiménez L, Sánchez-Mosquera P, Varela-Rey M, Martínez-Chantar ML, Anguita J, Ibrahim YH, Scaltriti M, Lawrie CH, Aransay AM, Iovanna JL, Baselga J, Caldas C, Barrio R, Serra V, Vivanco Md, Matheu A, Gomis RR, Carracedo A. Martín-Martín N, et al. Among authors: aldaz p. Nat Commun. 2016 Aug 24;7:12595. doi: 10.1038/ncomms12595. Nat Commun. 2016. PMID: 27553708 Free PMC article.
SOX9 Elevation Acts with Canonical WNT Signaling to Drive Gastric Cancer Progression.
Santos JC, Carrasco-Garcia E, Garcia-Puga M, Aldaz P, Montes M, Fernandez-Reyes M, de Oliveira CC, Lawrie CH, Araúzo-Bravo MJ, Ribeiro ML, Matheu A. Santos JC, et al. Among authors: aldaz p. Cancer Res. 2016 Nov 15;76(22):6735-6746. doi: 10.1158/0008-5472.CAN-16-1120. Epub 2016 Aug 28. Cancer Res. 2016. PMID: 27569216
Targeting SOX2 as a Therapeutic Strategy in Glioblastoma.
Garros-Regulez L, Garcia I, Carrasco-Garcia E, Lantero A, Aldaz P, Moreno-Cugnon L, Arrizabalaga O, Undabeitia J, Torres-Bayona S, Villanua J, Ruiz I, Egaña L, Sampron N, Matheu A. Garros-Regulez L, et al. Among authors: aldaz p. Front Oncol. 2016 Oct 24;6:222. doi: 10.3389/fonc.2016.00222. eCollection 2016. Front Oncol. 2016. PMID: 27822457 Free PMC article. Review.
Oncogenic activity of SOX1 in glioblastoma.
Garcia I, Aldaregia J, Marjanovic Vicentic J, Aldaz P, Moreno-Cugnon L, Torres-Bayona S, Carrasco-Garcia E, Garros-Regulez L, Egaña L, Rubio A, Pollard S, Stevanovic M, Sampron N, Matheu A. Garcia I, et al. Among authors: aldaz p. Sci Rep. 2017 Apr 20;7:46575. doi: 10.1038/srep46575. Sci Rep. 2017. PMID: 28425506 Free PMC article.
High expression of MKP1/DUSP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response.
Arrizabalaga O, Moreno-Cugnon L, Auzmendi-Iriarte J, Aldaz P, Ibanez de Caceres I, Garros-Regulez L, Moncho-Amor V, Torres-Bayona S, Pernía O, Pintado-Berninches L, Carrasco-Ramirez P, Cortes-Sempere M, Rosas R, Sanchez-Gomez P, Ruiz I, Caren H, Pollard S, Garcia I, Sacido AA, Lovell-Badge R, Belda-Iniesta C, Sampron N, Perona R, Matheu A. Arrizabalaga O, et al. Among authors: aldaz p. Oncogenesis. 2017 Dec 14;6(12):401. doi: 10.1038/s41389-017-0003-9. Oncogenesis. 2017. PMID: 29284798 Free PMC article.
PR-LncRNA signature regulates glioma cell activity through expression of SOX factors.
Torres-Bayona S, Aldaz P, Auzmendi-Iriarte J, Saenz-Antoñanzas A, Garcia I, Arrazola M, Gerovska D, Undabeitia J, Querejeta A, Egaña L, Villanúa J, Ruiz I, Sarasqueta C, Urculo E, Araúzo-Bravo MJ, Huarte M, Samprón N, Matheu A. Torres-Bayona S, et al. Among authors: aldaz p. Sci Rep. 2018 Aug 24;8(1):12746. doi: 10.1038/s41598-018-30836-5. Sci Rep. 2018. PMID: 30143669 Free PMC article.
45 results