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Tumor-associated macrophages impair NK cell IFN-γ production and contribute to tumor progression in clear cell renal cell carcinoma.
Núñez SY, Trotta A, Regge MV, Amarilla MS, Secchiari F, Sierra JM, Santilli MC, Gantov M, Rovegno A, Richards N, Ameri C, Ríos Pita H, Rico L, Mieggi M, Vitagliano G, Blas L, Friedrich AD, Domaica CI, Fuertes MB, Zwirner NW. Núñez SY, et al. Among authors: trotta a. Eur J Immunol. 2024 Apr 6:e2350878. doi: 10.1002/eji.202350878. Online ahead of print. Eur J Immunol. 2024. PMID: 38581345
Brucella abortus RNA does not polarize macrophages to a particular profile but interferes with M1 polarization.
Serafino A, Marin Franco JL, Maio M, Trotta A, Genoula M, Castillo LA, Birnberg Weiss F, Pittaluga JR, Balboa L, Barrionuevo P, Milillo MA. Serafino A, et al. Among authors: trotta a. PLoS Negl Trop Dis. 2022 Nov 28;16(11):e0010950. doi: 10.1371/journal.pntd.0010950. eCollection 2022 Nov. PLoS Negl Trop Dis. 2022. PMID: 36441810 Free PMC article.
The MICA-NKG2D axis in clear cell renal cell carcinoma bolsters MICA as target in immuno-oncology.
Secchiari F, Nuñez SY, Sierra JM, Ziblat A, Regge MV, Raffo Iraolagoitia XL, Rovegno A, Ameri C, Secin FP, Richards N, Ríos Pita H, Vitagliano G, Rico L, Mieggi M, Frascheri F, Bonanno N, Blas L, Trotta A, Friedrich AD, Fuertes MB, Domaica CI, Zwirner NW. Secchiari F, et al. Among authors: trotta a. Oncoimmunology. 2022 Aug 3;11(1):2104991. doi: 10.1080/2162402X.2022.2104991. eCollection 2022. Oncoimmunology. 2022. PMID: 35936986 Free PMC article.
Tumor-Experienced Human NK Cells Express High Levels of PD-L1 and Inhibit CD8+ T Cell Proliferation.
Sierra JM, Secchiari F, Nuñez SY, Iraolagoitia XLR, Ziblat A, Friedrich AD, Regge MV, Santilli MC, Torres NI, Gantov M, Trotta A, Ameri C, Vitagliano G, Pita HR, Rico L, Rovegno A, Richards N, Domaica CI, Zwirner NW, Fuertes MB. Sierra JM, et al. Among authors: trotta a. Front Immunol. 2021 Sep 20;12:745939. doi: 10.3389/fimmu.2021.745939. eCollection 2021. Front Immunol. 2021. PMID: 34616407 Free PMC article.
Brucella abortus-infected platelets modulate the activation of neutrophils.
Trotta A, Milillo MA, Serafino A, Castillo LA, Birnberg Weiss F, Delpino MV, Giambartolomei GH, Fernández GC, Barrionuevo P. Trotta A, et al. Immunol Cell Biol. 2020 Oct;98(9):743-756. doi: 10.1111/imcb.12373. Epub 2020 Aug 4. Immunol Cell Biol. 2020. PMID: 32623755
B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway.
Milillo MA, Velásquez LN, Trotta A, Delpino MV, Marinho FV, Balboa L, Vermeulen M, Espindola SL, Rodriguez-Rodrigues N, Fernández GC, Oliveira SC, Giambartolomei GH, Barrionuevo P. Milillo MA, et al. Among authors: trotta a. PLoS Pathog. 2017 Aug 2;13(8):e1006527. doi: 10.1371/journal.ppat.1006527. eCollection 2017 Aug. PLoS Pathog. 2017. PMID: 28767704 Free PMC article.
12 results