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Inhibition of the NLRP3 inflammasome prevents ovarian aging.
Navarro-Pando JM, Alcocer-Gómez E, Castejón-Vega B, Navarro-Villarán E, Condés-Hervás M, Mundi-Roldan M, Muntané J, Pérez-Pulido AJ, Bullon P, Wang C, Hoffman HM, Sanz A, Mbalaviele G, Ryffel B, Cordero MD. Navarro-Pando JM, et al. Among authors: alcocer gomez e. Sci Adv. 2021 Jan 1;7(1):eabc7409. doi: 10.1126/sciadv.abc7409. Print 2021 Jan. Sci Adv. 2021. PMID: 33523841 Free PMC article.
Stress-Induced NLRP3 Inflammasome in Human Diseases.
Alcocer-Gómez E, Castejón-Vega B, Cordero MD. Alcocer-Gómez E, et al. Adv Protein Chem Struct Biol. 2017;108:127-162. doi: 10.1016/bs.apcsb.2017.02.002. Epub 2017 Mar 27. Adv Protein Chem Struct Biol. 2017. PMID: 28427559 Review.
NLRP3 Inflammasome Inhibition by MCC950 in Aged Mice Improves Health via Enhanced Autophagy and PPARα Activity.
Marín-Aguilar F, Castejón-Vega B, Alcocer-Gómez E, Lendines-Cordero D, Cooper MA, de la Cruz P, Andújar-Pulido E, Pérez-Alegre M, Muntané J, Pérez-Pulido AJ, Ryffel B, Robertson AAB, Ruiz-Cabello J, Bullón P, Cordero MD. Marín-Aguilar F, et al. Among authors: alcocer gomez e. J Gerontol A Biol Sci Med Sci. 2020 Jul 13;75(8):1457-1464. doi: 10.1093/gerona/glz239. J Gerontol A Biol Sci Med Sci. 2020. PMID: 31603987
NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice.
Marín-Aguilar F, Lechuga-Vieco AV, Alcocer-Gómez E, Castejón-Vega B, Lucas J, Garrido C, Peralta-Garcia A, Pérez-Pulido AJ, Varela-López A, Quiles JL, Ryffel B, Flores I, Bullón P, Ruiz-Cabello J, Cordero MD. Marín-Aguilar F, et al. Among authors: alcocer gomez e. Aging Cell. 2020 Jan;19(1):e13050. doi: 10.1111/acel.13050. Epub 2019 Oct 18. Aging Cell. 2020. PMID: 31625260 Free PMC article.
Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice.
Cañadas-Lozano D, Marín-Aguilar F, Castejón-Vega B, Ryffel B, Navarro-Pando JM, Ruiz-Cabello J, Alcocer-Gómez E, Bullón P, Cordero MD. Cañadas-Lozano D, et al. Among authors: alcocer gomez e. Geroscience. 2020 Apr;42(2):715-725. doi: 10.1007/s11357-019-00151-6. Epub 2020 Jan 23. Geroscience. 2020. PMID: 31975052 Free PMC article.
Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson-Gilford Progeria.
González-Dominguez A, Montañez R, Castejón-Vega B, Nuñez-Vasco J, Lendines-Cordero D, Wang C, Mbalaviele G, Navarro-Pando JM, Alcocer-Gómez E, Cordero MD. González-Dominguez A, et al. Among authors: alcocer gomez e. EMBO Mol Med. 2021 Oct 7;13(10):e14012. doi: 10.15252/emmm.202114012. Epub 2021 Aug 27. EMBO Mol Med. 2021. PMID: 34448355 Free PMC article.
NLRP3 inflammasome: a new target in major depressive disorder.
Alcocer-Gómez E, Cordero MD. Alcocer-Gómez E, et al. CNS Neurosci Ther. 2014 Mar;20(3):294-5. doi: 10.1111/cns.12230. Epub 2014 Jan 31. CNS Neurosci Ther. 2014. PMID: 24479787 Free PMC article. No abstract available.
AMPK Phosphorylation Modulates Pain by Activation of NLRP3 Inflammasome.
Bullón P, Alcocer-Gómez E, Carrión AM, Marín-Aguilar F, Garrido-Maraver J, Román-Malo L, Ruiz-Cabello J, Culic O, Ryffel B, Apetoh L, Ghiringhelli F, Battino M, Sánchez-Alcazar JA, Cordero MD. Bullón P, et al. Antioxid Redox Signal. 2016 Jan 20;24(3):157-70. doi: 10.1089/ars.2014.6120. Epub 2015 Sep 16. Antioxid Redox Signal. 2016. PMID: 26132721 Free PMC article.
Stress-Induced Depressive Behaviors Require a Functional NLRP3 Inflammasome.
Alcocer-Gómez E, Ulecia-Morón C, Marín-Aguilar F, Rybkina T, Casas-Barquero N, Ruiz-Cabello J, Ryffel B, Apetoh L, Ghiringhelli F, Bullón P, Sánchez-Alcazar JA, Carrión AM, Cordero MD. Alcocer-Gómez E, et al. Mol Neurobiol. 2016 Sep;53(7):4874-82. doi: 10.1007/s12035-015-9408-7. Epub 2015 Sep 11. Mol Neurobiol. 2016. PMID: 26362308
Mutation in cytochrome b gene of mitochondrial DNA in a family with fibromyalgia is associated with NLRP3-inflammasome activation.
Cordero MD, Alcocer-Gómez E, Marín-Aguilar F, Rybkina T, Cotán D, Pérez-Pulido A, Alvarez-Suarez JM, Battino M, Sánchez-Alcazar JA, Carrión AM, Culic O, Navarro-Pando JM, Bullón P. Cordero MD, et al. J Med Genet. 2016 Feb;53(2):113-22. doi: 10.1136/jmedgenet-2015-103392. Epub 2015 Nov 13. J Med Genet. 2016. PMID: 26566881
49 results