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Chalcones: a valid scaffold for monoamine oxidases inhibitors.
Chimenti F, Fioravanti R, Bolasco A, Chimenti P, Secci D, Rossi F, Yáñez M, Orallo F, Ortuso F, Alcaro S. Chimenti F, et al. Among authors: alcaro s. J Med Chem. 2009 May 14;52(9):2818-24. doi: 10.1021/jm801590u. J Med Chem. 2009. PMID: 19378991
Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B.
Distinto S, Yáñez M, Alcaro S, Cardia MC, Gaspari M, Sanna ML, Meleddu R, Ortuso F, Kirchmair J, Markt P, Bolasco A, Wolber G, Secci D, Maccioni E. Distinto S, et al. Among authors: alcaro s. Eur J Med Chem. 2012 Feb;48:284-95. doi: 10.1016/j.ejmech.2011.12.027. Epub 2011 Dec 24. Eur J Med Chem. 2012. PMID: 22222137
New insights into the biological properties of Crocus sativus L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies.
De Monte C, Carradori S, Chimenti P, Secci D, Mannina L, Alcaro F, Petzer A, N'Da CI, Gidaro MC, Costa G, Alcaro S, Petzer JP. De Monte C, et al. Among authors: alcaro f, alcaro s. Eur J Med Chem. 2014 Jul 23;82:164-71. doi: 10.1016/j.ejmech.2014.05.048. Epub 2014 May 22. Eur J Med Chem. 2014. PMID: 24904963
(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro-1H-indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase.
Meleddu R, Distinto S, Corona A, Bianco G, Cannas V, Esposito F, Artese A, Alcaro S, Matyus P, Bogdan D, Cottiglia F, Tramontano E, Maccioni E. Meleddu R, et al. Among authors: alcaro s. Eur J Med Chem. 2015 Mar 26;93:452-60. doi: 10.1016/j.ejmech.2015.02.032. Epub 2015 Feb 20. Eur J Med Chem. 2015. PMID: 25728026
Drug design, synthesis, in vitro and in silico evaluation of selective monoaminoxidase B inhibitors based on 3-acetyl-2-dichlorophenyl-5-aryl-2,3-dihydro-1,3,4-oxadiazole chemical scaffold.
Distinto S, Meleddu R, Yanez M, Cirilli R, Bianco G, Sanna ML, Arridu A, Cossu P, Cottiglia F, Faggi C, Ortuso F, Alcaro S, Maccioni E. Distinto S, et al. Among authors: alcaro s. Eur J Med Chem. 2016 Jan 27;108:542-552. doi: 10.1016/j.ejmech.2015.12.026. Epub 2015 Dec 17. Eur J Med Chem. 2016. PMID: 26717204
263 results