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A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies.
Wang C, van Haperen R, Gutiérrez-Álvarez J, Li W, Okba NMA, Albulescu I, Widjaja I, van Dieren B, Fernandez-Delgado R, Sola I, Hurdiss DL, Daramola O, Grosveld F, van Kuppeveld FJM, Haagmans BL, Enjuanes L, Drabek D, Bosch BJ. Wang C, et al. Nat Commun. 2021 Mar 17;12(1):1715. doi: 10.1038/s41467-021-21968-w. Nat Commun. 2021. PMID: 33731724 Free PMC article.
An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces protective immunity and prevents transmission of SARS-CoV-2 between cats.
Langereis MA, Albulescu IC, Stammen-Vogelzangs J, Lambregts M, Stachura K, Miller S, Bosco-Lauth AM, Hartwig AE, Porter SM, Allen M, Mogler M, van Kuppeveld FJM, Bosch BJ, Vermeij P, de Groof A, Bowen RA, Davis R, Xu Z, Tarpey I. Langereis MA, et al. Among authors: albulescu ic. NPJ Vaccines. 2021 Oct 20;6(1):122. doi: 10.1038/s41541-021-00390-9. NPJ Vaccines. 2021. PMID: 34671047 Free PMC article.
Intranasal administration of a live-attenuated recombinant newcastle disease virus expressing the SARS-CoV-2 Spike protein induces high neutralizing antibody levels and protects from experimental challenge infection in hamsters.
de Swart RL, de Leeuw OS, Oreshkova N, Gerhards NM, Albulescu IC, Vreman S, Gonzales JL, Maas R, van Kuppeveld FJM, Soema P, Bosch BJ, Peeters BPH. de Swart RL, et al. Among authors: albulescu ic. Vaccine. 2022 Aug 5;40(33):4676-4681. doi: 10.1016/j.vaccine.2022.07.005. Epub 2022 Jul 6. Vaccine. 2022. PMID: 35820941 Free PMC article.
The viral capping enzyme nsP1: a novel target for the inhibition of chikungunya virus infection.
Delang L, Li C, Tas A, Quérat G, Albulescu IC, De Burghgraeve T, Guerrero NA, Gigante A, Piorkowski G, Decroly E, Jochmans D, Canard B, Snijder EJ, Pérez-Pérez MJ, van Hemert MJ, Coutard B, Leyssen P, Neyts J. Delang L, et al. Among authors: albulescu ic. Sci Rep. 2016 Aug 22;6:31819. doi: 10.1038/srep31819. Sci Rep. 2016. PMID: 27545976 Free PMC article.
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