Alblihy A - Search Results

1

FEN1 Blockade for Platinum Chemo-Sensitization and Synthetic Lethality in Epithelial Ovarian Cancers.

Mesquita KA, Ali R, Doherty R, Toss MS, Miligy I, Alblihy A, Dorjsuren D, Simeonov A, Jadhav A, Wilson DM 3rd, Hickson I, Tatum NJ, Rakha EA, Madhusudan S. Mesquita KA, et al. Among authors: alblihy a. Cancers (Basel). 2021 Apr 14;13(8):1866. doi: 10.3390/cancers13081866. Cancers (Basel). 2021. PMID: 33919707 Free PMC article.

2

ERCC1-XPF deficiency is a predictor of olaparib induced synthetic lethality and platinum sensitivity in epithelial ovarian cancers.

Mesquita KA, Alabdullah M, Griffin M, Toss MS, Fatah TMAA, Alblihy A, Moseley P, Chan SYT, Rakha EA, Madhusudan S. Mesquita KA, et al. Among authors: alblihy a. Gynecol Oncol. 2019 May;153(2):416-424. doi: 10.1016/j.ygyno.2019.02.014. Epub 2019 Feb 21. Gynecol Oncol. 2019. PMID: 30797591

3

PARP1 blockade is synthetically lethal in XRCC1 deficient sporadic epithelial ovarian cancers.

Ali R, Alabdullah M, Alblihy A, Miligy I, Mesquita KA, Chan SY, Moseley P, Rakha EA, Madhusudan S. Ali R, et al. Among authors: alblihy a. Cancer Lett. 2020 Jan 28;469:124-133. doi: 10.1016/j.canlet.2019.10.035. Epub 2019 Oct 24. Cancer Lett. 2020. PMID: 31669203

4

XRCC1 deficient triple negative breast cancers are sensitive to ATR, ATM and Wee1 inhibitor either alone or in combination with olaparib.

Ali R, Alblihy A, Toss MS, Algethami M, Al Sunni R, Green AR, Rakha EA, Madhusudan S. Ali R, et al. Among authors: alblihy a. Ther Adv Med Oncol. 2020 Dec 21;12:1758835920974201. doi: 10.1177/1758835920974201. eCollection 2020. Ther Adv Med Oncol. 2020. PMID: 33425022 Free PMC article.

5

Clinicopathological and Functional Evaluation Reveal NBS1 as a Predictor of Platinum Resistance in Epithelial Ovarian Cancers.

Alblihy A, Alabdullah ML, Ali R, Algethami M, Toss MS, Mongan NP, Rakha EA, Madhusudan S. Alblihy A, et al. Biomedicines. 2021 Jan 8;9(1):56. doi: 10.3390/biomedicines9010056. Biomedicines. 2021. PMID: 33435622 Free PMC article.

6

Molecular disruption of DNA polymerase β for platinum sensitisation and synthetic lethality in epithelial ovarian cancers.

Ali R, Alblihy A, Miligy IM, Alabdullah ML, Alsaleem M, Toss MS, Algethami M, Abdel-Fatah T, Moseley P, Chan S, Mongan NP, Narayan S, Rakha EA, Madhusudan S. Ali R, et al. Among authors: alblihy a. Oncogene. 2021 Apr;40(14):2496-2508. doi: 10.1038/s41388-021-01710-y. Epub 2021 Mar 5. Oncogene. 2021. PMID: 33674744 Free PMC article.

7

Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 deficient epithelial ovarian cancers.

Ali R, Alabdullah M, Algethami M, Alblihy A, Miligy I, Shoqafi A, Mesquita KA, Abdel-Fatah T, Chan SY, Chiang PW, Mongan NP, Rakha EA, Tomkinson AE, Madhusudan S. Ali R, et al. Among authors: alblihy a. Theranostics. 2021 Jul 25;11(17):8350-8361. doi: 10.7150/thno.51456. eCollection 2021. Theranostics. 2021. PMID: 34373746 Free PMC article.

8

Untangling the clinicopathological significance of MRE11-RAD50-NBS1 complex in sporadic breast cancers.

Alblihy A, Shoqafi A, Toss MS, Algethami M, Harris AE, Jeyapalan JN, Abdel-Fatah T, Servante J, Chan SYT, Green A, Mongan NP, Rakha EA, Madhusudan S. Alblihy A, et al. NPJ Breast Cancer. 2021 Nov 15;7(1):143. doi: 10.1038/s41523-021-00350-5. NPJ Breast Cancer. 2021. PMID: 34782604 Free PMC article.

9

RAD50 deficiency is a predictor of platinum sensitivity in sporadic epithelial ovarian cancers.

Alblihy A, Alabdullah ML, Toss MS, Algethami M, Mongan NP, Rakha EA, Madhusudan S. Alblihy A, et al. Mol Biomed. 2020 Dec 30;1(1):19. doi: 10.1186/s43556-020-00023-y. Mol Biomed. 2020. PMID: 35006434 Free PMC article.

10

Targeting Mre11 overcomes platinum resistance and induces synthetic lethality in XRCC1 deficient epithelial ovarian cancers.

Alblihy A, Ali R, Algethami M, Shoqafi A, Toss MS, Brownlie J, Tatum NJ, Hickson I, Moran PO, Grabowska A, Jeyapalan JN, Mongan NP, Rakha EA, Madhusudan S. Alblihy A, et al. NPJ Precis Oncol. 2022 Jul 19;6(1):51. doi: 10.1038/s41698-022-00298-0. NPJ Precis Oncol. 2022. PMID: 35853939 Free PMC article.

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