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The LSD1 inhibitor iadademstat (ORY-1001) targets SOX2-driven breast cancer stem cells: a potential epigenetic therapy in luminal-B and HER2-positive breast cancer subtypes.
Cuyàs E, Gumuzio J, Verdura S, Brunet J, Bosch-Barrera J, Martin-Castillo B, Alarcón T, Encinar JA, Martin ÁG, Menendez JA. Cuyàs E, et al. Among authors: alarcon t. Aging (Albany NY). 2020 Mar 18;12(6):4794-4814. doi: 10.18632/aging.102887. Epub 2020 Mar 18. Aging (Albany NY). 2020. PMID: 32191225 Free PMC article.
The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells.
Menendez JA, Joven J, Cufí S, Corominas-Faja B, Oliveras-Ferraros C, Cuyàs E, Martin-Castillo B, López-Bonet E, Alarcón T, Vazquez-Martin A. Menendez JA, et al. Among authors: alarcon t. Cell Cycle. 2013 Apr 15;12(8):1166-79. doi: 10.4161/cc.24479. Epub 2013 Apr 2. Cell Cycle. 2013. PMID: 23549172 Free PMC article.
Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway.
Corominas-Faja B, Cufí S, Oliveras-Ferraros C, Cuyàs E, López-Bonet E, Lupu R, Alarcón T, Vellon L, Iglesias JM, Leis O, Martín ÁG, Vazquez-Martin A, Menendez JA. Corominas-Faja B, et al. Among authors: alarcon t. Cell Cycle. 2013 Sep 15;12(18):3109-24. doi: 10.4161/cc.26173. Epub 2013 Aug 21. Cell Cycle. 2013. PMID: 23974095 Free PMC article.
Metabostemness: a new cancer hallmark.
Menendez JA, Alarcón T. Menendez JA, et al. Among authors: alarcon t. Front Oncol. 2014 Sep 29;4:262. doi: 10.3389/fonc.2014.00262. eCollection 2014. Front Oncol. 2014. PMID: 25325014 Free PMC article. Review.
Oncometabolic Nuclear Reprogramming of Cancer Stemness.
Menendez JA, Corominas-Faja B, Cuyàs E, García MG, Fernández-Arroyo S, Fernández AF, Joven J, Fraga MF, Alarcón T. Menendez JA, et al. Among authors: alarcon t. Stem Cell Reports. 2016 Mar 8;6(3):273-83. doi: 10.1016/j.stemcr.2015.12.012. Epub 2016 Feb 11. Stem Cell Reports. 2016. PMID: 26876667 Free PMC article.
271 results