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Adaptation of transgene mRNA translation boosts the anticancer efficacy of oncolytic HSV1.
Hoang HD, Said A, Vaidya N, Gilchrist VH, Malone K, Kabilan U, Topshee S, Xiang X, Yang AD, Olagnier D, Mossman K, Beug ST, Jafarnejad SM, Workenhe ST, Graber TE, Alain T. Hoang HD, et al. Among authors: alain t. J Immunother Cancer. 2023 Mar;11(3):e006408. doi: 10.1136/jitc-2022-006408. J Immunother Cancer. 2023. PMID: 36958764 Free PMC article.
Distinct perturbation of the translatome by the antidiabetic drug metformin.
Larsson O, Morita M, Topisirovic I, Alain T, Blouin MJ, Pollak M, Sonenberg N. Larsson O, et al. Among authors: alain t. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8977-82. doi: 10.1073/pnas.1201689109. Epub 2012 May 18. Proc Natl Acad Sci U S A. 2012. PMID: 22611195 Free PMC article.
Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling.
Fonseca BD, Diering GH, Bidinosti MA, Dalal K, Alain T, Balgi AD, Forestieri R, Nodwell M, Rajadurai CV, Gunaratnam C, Tee AR, Duong F, Andersen RJ, Orlowski J, Numata M, Sonenberg N, Roberge M. Fonseca BD, et al. Among authors: alain t. J Biol Chem. 2012 May 18;287(21):17530-17545. doi: 10.1074/jbc.M112.359638. Epub 2012 Apr 2. J Biol Chem. 2012. PMID: 22474287 Free PMC article.
Pharmacological and genetic evaluation of proposed roles of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK), extracellular signal-regulated kinase (ERK), and p90(RSK) in the control of mTORC1 protein signaling by phorbol esters.
Fonseca BD, Alain T, Finestone LK, Huang BP, Rolfe M, Jiang T, Yao Z, Hernandez G, Bennett CF, Proud CG. Fonseca BD, et al. Among authors: alain t. J Biol Chem. 2011 Aug 5;286(31):27111-22. doi: 10.1074/jbc.M111.260794. Epub 2011 Jun 9. J Biol Chem. 2011. PMID: 21659537 Free PMC article.
Reovirus therapy of lymphoid malignancies.
Alain T, Hirasawa K, Pon KJ, Nishikawa SG, Urbanski SJ, Auer Y, Luider J, Martin A, Johnston RN, Janowska-Wieczorek A, Lee PW, Kossakowska AE. Alain T, et al. Blood. 2002 Dec 1;100(12):4146-53. doi: 10.1182/blood-2002-02-0503. Epub 2002 Jul 25. Blood. 2002. PMID: 12393565 Free article.
Leukocyte elastase in murine and human non-Hodgkin lymphomas.
De Noncourt P, Robledo O, Alain T, Kossakowska AE, Urbanski SJ, Potworowski EF, St-Pierre Y. De Noncourt P, et al. Among authors: alain t. J Leukoc Biol. 2001 Oct;70(4):585-91. J Leukoc Biol. 2001. PMID: 11590195
112 results