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GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity.
Heitzeneder S, Bosse KR, Zhu Z, Zhelev D, Majzner RG, Radosevich MT, Dhingra S, Sotillo E, Buongervino S, Pascual-Pasto G, Garrigan E, Xu P, Huang J, Salzer B, Delaidelli A, Raman S, Cui H, Martinez B, Bornheimer SJ, Sahaf B, Alag A, Fetahu IS, Hasselblatt M, Parker KR, Anbunathan H, Hwang J, Huang M, Sakamoto K, Lacayo NJ, Klysz DD, Theruvath J, Vilches-Moure JG, Satpathy AT, Chang HY, Lehner M, Taschner-Mandl S, Julien JP, Sorensen PH, Dimitrov DS, Maris JM, Mackall CL. Heitzeneder S, et al. Among authors: alag a. Cancer Cell. 2022 Jan 10;40(1):53-69.e9. doi: 10.1016/j.ccell.2021.12.005. Epub 2021 Dec 30. Cancer Cell. 2022. PMID: 34971569 Free PMC article.
Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion.
Heitzeneder S, Sotillo E, Shern JF, Sindiri S, Xu P, Jones R, Pollak M, Noer PR, Lorette J, Fazli L, Alag A, Meltzer P, Lau C, Conover CA, Oxvig C, Sorensen PH, Maris JM, Khan J, Mackall CL. Heitzeneder S, et al. Among authors: alag a. J Natl Cancer Inst. 2019 Sep 1;111(9):970-982. doi: 10.1093/jnci/djy209. J Natl Cancer Inst. 2019. PMID: 30698726 Free PMC article.
How autoreactive thymocytes differentiate into regulatory versus effector CD4+ T cells after avoiding clonal deletion.
Tai X, Indart A, Rojano M, Guo J, Apenes N, Kadakia T, Craveiro M, Alag A, Etzensperger R, Badr ME, Zhang F, Zhang Z, Mu J, Guinter T, Crossman A, Granger L, Sharrow S, Zhou X, Singer A. Tai X, et al. Among authors: alag a. Nat Immunol. 2023 Apr;24(4):637-651. doi: 10.1038/s41590-023-01469-2. Epub 2023 Mar 23. Nat Immunol. 2023. PMID: 36959291 Free PMC article.
Novel Cluster AZ Arthrobacter phages Powerpuff, Lego, and YesChef exhibit close functional relationships with Microbacterium phages.
Kapinos A, Aghamalian P, Capehart E, Alag A, Angel H, Briseno E, Corado Perez B, Farag E, Foster H, Hakim A, Hernandez-Casas D, Huang C, Lam D, Mendez M, Min A, Nguyen N, Omholt AL, Ortiz E, Saldivar LS, Shannon JA, Smith R, Sridhar MV, Ta A, Theophilus MC, Ngo R, Torres C, Reddi K, Freise AC, Moberg Parker J. Kapinos A, et al. Among authors: alag a. PLoS One. 2022 Jan 13;17(1):e0262556. doi: 10.1371/journal.pone.0262556. eCollection 2022. PLoS One. 2022. PMID: 35025964 Free PMC article.
18 results