Al-Najjar BO - Search Results

1

Unlocking the Conformational Changes of P2Y₁₂: Exploring an Acridinone Compound's Effect on Receptor Activity and Conformation.

Al-Najjar BO, Saqallah FG. Al-Najjar BO, et al. Molecules. 2023 May 4;28(9):3878. doi: 10.3390/molecules28093878. Molecules. 2023. PMID: 37175288 Free PMC article.

2

P2Y₁₂ antagonists: Approved drugs, potential naturally isolated and synthesised compounds, and related in-silico studies.

Al-Najjar BO, Saqallah FG, Abbas MA, Al-Hijazeen SZ, Sibai OA. Al-Najjar BO, et al. Eur J Med Chem. 2022 Jan 5;227:113924. doi: 10.1016/j.ejmech.2021.113924. Epub 2021 Oct 22. Eur J Med Chem. 2022. PMID: 34731765 Review.

3

QSAR, structure-based pharmacophore modelling and biological evaluation of novel platelet ADP receptor (P2Y₁₂) antagonist.

Al-Najjar BO, Abbas MA, Sibai OA, Saqallah FG, Al-Kabariti AY. Al-Najjar BO, et al. RSC Med Chem. 2022 Nov 22;14(2):239-246. doi: 10.1039/d2md00285j. eCollection 2023 Feb 22. RSC Med Chem. 2022. PMID: 36846363 Free PMC article.

4

Structure-Based Drug Design Studies Toward the Discovery of Novel Chalcone Derivatives as Potential Epidermal Growth Factor Receptor (EGFR) Inhibitors.

Al-Anazi M, Al-Najjar BO, Khairuddean M. Al-Anazi M, et al. Among authors: al najjar bo. Molecules. 2018 Dec 5;23(12):3203. doi: 10.3390/molecules23123203. Molecules. 2018. PMID: 30563058 Free PMC article.

5

Investigation of 15-hydroxyprostaglandin dehydrogenase catalytic reaction mechanism by molecular dynamics simulations.

Al-Najjar BO. Al-Najjar BO. J Mol Graph Model. 2018 Mar;80:190-196. doi: 10.1016/j.jmgm.2018.01.012. J Mol Graph Model. 2018. PMID: 29414038

6

Arylamide as Potential Selective Inhibitor for Matrix Metalloproteinase 9 (MMP9): Design, Synthesis, Biological Evaluation, and Molecular Modeling.

Hariono M, Nuwarda RF, Yusuf M, Rollando R, Jenie RI, Al-Najjar B, Julianus J, Putra KC, Nugroho ES, Wisnumurti YK, Dewa SP, Jati BW, Tiara R, Ramadani RD, Qodria L, Wahab HA. Hariono M, et al. J Chem Inf Model. 2020 Jan 27;60(1):349-359. doi: 10.1021/acs.jcim.9b00630. Epub 2019 Dec 26. J Chem Inf Model. 2020. PMID: 31825614

7

Identification of potential dual -targets anti- toxoplasma gondii compounds through structure-based virtual screening and in-vitro studies.

Salin NH, Noordin R, Al-Najjar BO, Kamarulzaman EE, Yunus MH, Karim IZA, Nasim NNM, Zakaria II, Wahab HA. Salin NH, et al. Among authors: al najjar bo. PLoS One. 2020 May 22;15(5):e0225232. doi: 10.1371/journal.pone.0225232. eCollection 2020. PLoS One. 2020. PMID: 32442170 Free PMC article.

8

Antinociceptive Action of Moringa peregrina is Mediated by an Interaction with α₂-Adrenergic Receptor.

Jaffal SM, Al-Najjar BO, Abbas MA, Oran SA. Jaffal SM, et al. Among authors: al najjar bo. Balkan Med J. 2020 Jun 1;37(4):189-195. doi: 10.4274/balkanmedj.galenos.2020.2019.11.14. Epub 2020 Mar 4. Balkan Med J. 2020. PMID: 32126746 Free PMC article.

9

Hypolipidaemic and Insulin Secretagogue Activities of (R)-(-)-Carvone.

Abbas MA, Oriquat GA, Abbas MM, Al-Najjar BO, Kandil YI. Abbas MA, et al. Among authors: al najjar bo. Malays J Med Sci. 2020 Dec;27(6):39-52. doi: 10.21315/mjms2020.27.6.5. Epub 2020 Dec 29. Malays J Med Sci. 2020. PMID: 33447133 Free PMC article.

10

Ononis spinosa alleviated capsaicin-induced mechanical allodynia in a rat model through transient receptor potential vanilloid 1 modulation.

Jaffal SM, Al-Najjar BO, Abbas MA. Jaffal SM, et al. Among authors: al najjar bo. Korean J Pain. 2021 Jul 1;34(3):262-270. doi: 10.3344/kjp.2021.34.3.262. Korean J Pain. 2021. PMID: 34193633 Free PMC article.

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