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Target 2035 - update on the quest for a probe for every protein.
Müller S, Ackloo S, Al Chawaf A, Al-Lazikani B, Antolin A, Baell JB, Beck H, Beedie S, Betz UAK, Bezerra GA, Brennan PE, Brown D, Brown PJ, Bullock AN, Carter AJ, Chaikuad A, Chaineau M, Ciulli A, Collins I, Dreher J, Drewry D, Edfeldt K, Edwards AM, Egner U, Frye SV, Fuchs SM, Hall MD, Hartung IV, Hillisch A, Hitchcock SH, Homan E, Kannan N, Kiefer JR, Knapp S, Kostic M, Kubicek S, Leach AR, Lindemann S, Marsden BD, Matsui H, Meier JL, Merk D, Michel M, Morgan MR, Mueller-Fahrnow A, Owen DR, Perry BG, Rosenberg SH, Saikatendu KS, Schapira M, Scholten C, Sharma S, Simeonov A, Sundström M, Superti-Furga G, Todd MH, Tredup C, Vedadi M, von Delft F, Willson TM, Winter GE, Workman P, Arrowsmith CH. Müller S, et al. Among authors: al lazikani b. RSC Med Chem. 2021 Dec 3;13(1):13-21. doi: 10.1039/d1md00228g. eCollection 2022 Jan 27. RSC Med Chem. 2021. PMID: 35211674 Free PMC article.
Objective assessment of cancer genes for drug discovery.
Patel MN, Halling-Brown MD, Tym JE, Workman P, Al-Lazikani B. Patel MN, et al. Nat Rev Drug Discov. 2013 Jan;12(1):35-50. doi: 10.1038/nrd3913. Nat Rev Drug Discov. 2013. PMID: 23274470 Review.
Drugging cancer genomes.
Workman P, Al-Lazikani B. Workman P, et al. Nat Rev Drug Discov. 2013 Dec;12(12):889-90. doi: 10.1038/nrd4184. Nat Rev Drug Discov. 2013. PMID: 24287764 No abstract available.
canSAR: an updated cancer research and drug discovery knowledgebase.
Tym JE, Mitsopoulos C, Coker EA, Razaz P, Schierz AC, Antolin AA, Al-Lazikani B. Tym JE, et al. Nucleic Acids Res. 2016 Jan 4;44(D1):D938-43. doi: 10.1093/nar/gkv1030. Epub 2015 Dec 15. Nucleic Acids Res. 2016. PMID: 26673713 Free PMC article.
Distinctive Behaviors of Druggable Proteins in Cellular Networks.
Mitsopoulos C, Schierz AC, Workman P, Al-Lazikani B. Mitsopoulos C, et al. PLoS Comput Biol. 2015 Dec 23;11(12):e1004597. doi: 10.1371/journal.pcbi.1004597. eCollection 2015 Dec. PLoS Comput Biol. 2015. PMID: 26699810 Free PMC article.
72 results