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MAS-related G protein-coupled receptors X (MRGPRX): Orphan GPCRs with potential as targets for future drugs.
Pharmacol Ther. 2022 Oct;238:108259. doi: 10.1016/j.pharmthera.2022.108259. Epub 2022 Aug 5.
Pharmacol Ther. 2022.
PMID: 35934214
Review.
Targeting the Main Protease of SARS-CoV-2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors.
Breidenbach J, Lemke C, Pillaiyar T, Schäkel L, Al Hamwi G, Diett M, Gedschold R, Geiger N, Lopez V, Mirza S, Namasivayam V, Schiedel AC, Sylvester K, Thimm D, Vielmuth C, Phuong Vu L, Zyulina M, Bodem J, Gütschow M, Müller CE.
Breidenbach J, et al. Among authors: al hamwi g.
Angew Chem Int Ed Engl. 2021 Apr 26;60(18):10423-10429. doi: 10.1002/anie.202016961. Epub 2021 Mar 24.
Angew Chem Int Ed Engl. 2021.
PMID: 33655614
Free PMC article.
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Discovery of Potent Agonists for the Predominant Variant of the Orphan MAS-Related G Protein-Coupled Receptor X4 (MRGPRX4).
Marx D, Alnouri MW, Clemens S, Gedschold R, Riedel Y, Al Hamwi G, Pillaiyar T, Hockemeyer J, Namasivayam V, Müller CE.
Marx D, et al. Among authors: al hamwi g.
J Med Chem. 2023 Dec 14;66(23):15674-15698. doi: 10.1021/acs.jmedchem.3c01013. Epub 2023 Nov 15.
J Med Chem. 2023.
PMID: 37967029
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Proinflammatory chemokine CXCL14 activates MAS-related G protein-coupled receptor MRGPRX2 and its putative mouse ortholog MRGPRB2.
Al Hamwi G, Namasivayam V, Büschbell B, Gedschold R, Golz S, Müller CE.
Al Hamwi G, et al.
Commun Biol. 2024 Jan 6;7(1):52. doi: 10.1038/s42003-023-05739-5.
Commun Biol. 2024.
PMID: 38184723
Free PMC article.
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