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The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity. Cysteine 866 and histidine 881 are essential for enzyme activity.
Schmidt G, Selzer J, Lerm M, Aktories K. Schmidt G, et al. Among authors: aktories k. J Biol Chem. 1998 May 29;273(22):13669-74. doi: 10.1074/jbc.273.22.13669. J Biol Chem. 1998. PMID: 9593707 Free article.
Recently, it has been reported that cytotoxic necrotizing factor 1 (CNF1) from Escherichia coli induces formation of stress fibers by deamidation of glutamine 63 of RhoA (Schmidt, G., Sehr, P., Wilm, M., Selzer, J., Mann, M., and Aktories, K. (1997) Nature 387, 725- …
Recently, it has been reported that cytotoxic necrotizing factor 1 (CNF1) from Escherichia coli induces formation of stress fibers by deamid …
Bacterial cytotoxins target Rho GTPases.
Schmidt G, Aktories K. Schmidt G, et al. Among authors: aktories k. Naturwissenschaften. 1998 Jun;85(6):253-61. doi: 10.1007/s001140050495. Naturwissenschaften. 1998. PMID: 9686394 Review.
456 results