Akssira M - Search Results

1

Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors.

Ouach A, Boulahjar R, Vala C, Bourg S, Bonnet P, Guguen-Guillouzo C, Ravache M, Le Guevel R, Lozach O, Lazar S, Troin Y, Meijer L, Ruchaud S, Akssira M, Guillaumet G, Routier S. Ouach A, et al. Among authors: akssira m. Eur J Med Chem. 2016 Jun 10;115:311-25. doi: 10.1016/j.ejmech.2016.02.072. Epub 2016 Mar 2. Eur J Med Chem. 2016. PMID: 27019296

2

New efficient route to dissymmetric 2,4-di(het)aryl-pyrido[3,2-d]pyrimidines via regioselective cross-coupling reactions.

Tikad A, Routier S, Akssira M, Leger JM, Jarry C, Guillaumet G. Tikad A, et al. Among authors: akssira m. Org Lett. 2007 Nov 8;9(23):4673-6. doi: 10.1021/ol7014434. Epub 2007 Oct 20. Org Lett. 2007. PMID: 17949094

3

Efficient one-pot synthesis of 2,4-di(het)aryl and 2,4-diamino pyrido[3,2-d]pyrimidines involving regioselective S(N)Ar and palladium-catalyzed reactions.

Tikad A, Routier S, Akssira M, Guillaumet G. Tikad A, et al. Among authors: akssira m. Org Biomol Chem. 2009 Dec 21;7(24):5113-8. doi: 10.1039/b913657f. Epub 2009 Oct 15. Org Biomol Chem. 2009. PMID: 20024106

4

Novel tetrahydropyrido[1,2-a]isoindolone derivatives (valmerins): potent cyclin-dependent kinase/glycogen synthase kinase 3 inhibitors with antiproliferative activities and antitumor effects in human tumor xenografts.

Boulahjar R, Ouach A, Matteo C, Bourg S, Ravache M, le Guével R, Marionneau S, Oullier T, Lozach O, Meijer L, Guguen-Guillouzo C, Lazar S, Akssira M, Troin Y, Guillaumet G, Routier S. Boulahjar R, et al. Among authors: akssira m. J Med Chem. 2012 Nov 26;55(22):9589-606. doi: 10.1021/jm3008536. Epub 2012 Nov 1. J Med Chem. 2012. PMID: 23083119

5

Design, synthesis, and biological activity of pyridopyrimidine scaffolds as novel PI3K/mTOR dual inhibitors.

Saurat T, Buron F, Rodrigues N, de Tauzia ML, Colliandre L, Bourg S, Bonnet P, Guillaumet G, Akssira M, Corlu A, Guillouzo C, Berthier P, Rio P, Jourdan ML, Bénédetti H, Routier S. Saurat T, et al. Among authors: akssira m. J Med Chem. 2014 Feb 13;57(3):613-31. doi: 10.1021/jm401138v. Epub 2014 Jan 21. J Med Chem. 2014. PMID: 24345273

6

Synthesis and biological evaluation of 9α- and 9β-hydroxyamino-parthenolides as novel anticancer agents.

Moumou M, El Bouakher A, Allouchi H, El Hakmaoui A, Benharref A, Mathieu V, Guillaumet G, Akssira M. Moumou M, et al. Among authors: akssira m. Bioorg Med Chem Lett. 2014 Aug 15;24(16):4014-8. doi: 10.1016/j.bmcl.2014.06.019. Epub 2014 Jun 14. Bioorg Med Chem Lett. 2014. PMID: 24998377

7

Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors.

Boulahjar R, Ouach A, Bourg S, Bonnet P, Lozach O, Meijer L, Guguen-Guillouzo C, Le Guevel R, Lazar S, Akssira M, Troin Y, Guillaumet G, Routier S. Boulahjar R, et al. Among authors: akssira m. Eur J Med Chem. 2015 Aug 28;101:274-87. doi: 10.1016/j.ejmech.2015.06.046. Epub 2015 Jun 27. Eur J Med Chem. 2015. PMID: 26142492 Free article.

8

Synthetic Modification of 9α- and 9β-Hydroxyparthenolide by Heck or Acylation Reactions and Evaluation of Cytotoxic Activities.

El Bouakher A, Jismy B, Allouchi H, Duverger E, Barkaoui L, El Hakmaoui A, Daniellou R, Guillaumet G, Akssira M. El Bouakher A, et al. Among authors: akssira m. Planta Med. 2017 May;83(7):661-671. doi: 10.1055/s-0042-119864. Epub 2016 Dec 5. Planta Med. 2017. PMID: 27919107

9

Efficient synthesis and first regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold and their evaluation in H₂O₂-induced oxidative stress.

Loubidi M, Jouha J, Tber Z, Khouili M, Suzenet F, Akssira M, Erdogan MA, Köse FA, Dagcı T, Armagan G, Saso L, Guillaumet G. Loubidi M, et al. Among authors: akssira m. Eur J Med Chem. 2018 Feb 10;145:113-123. doi: 10.1016/j.ejmech.2017.12.081. Epub 2017 Dec 27. Eur J Med Chem. 2018. PMID: 29324335

10

Regioselective Synthesis of New 2,4-(Het)aryl-3H-pyrido[1',2':1,5]pyrazolo[4,3-d]pyrimidines Involving Palladium-Catalyzed Cross-Coupling Reactions.

Ejjoummany A, Belaroussi R, El Hakmaoui A, Akssira M, Guillaumet G, Buron F, Routier S. Ejjoummany A, et al. Among authors: akssira m. Molecules. 2018 Oct 23;23(11):2740. doi: 10.3390/molecules23112740. Molecules. 2018. PMID: 30360579 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

74 results

Search Page