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Presence of novel compound BCR-ABL mutations in late chronic and advanced phase imatinib sensitive CML patients indicates their possible role in CML progression.
Akram AM, Iqbal Z, Akhtar T, Khalid AM, Sabar MF, Qazi MH, Aziz Z, Sajid N, Aleem A, Rasool M, Asif M, Aloraibi S, Aljamaan K, Iqbal M. Akram AM, et al. Cancer Biol Ther. 2017 Apr 3;18(4):214-221. doi: 10.1080/15384047.2017.1294289. Epub 2017 Feb 21. Cancer Biol Ther. 2017. PMID: 28278078 Free PMC article.
Prognostically significant fusion oncogenes in Pakistani patients with adult acute lymphoblastic leukemia and their association with disease biology and outcome.
Sabir N, Iqbal Z, Aleem A, Awan T, Naeem T, Asad S, Tahir AH, Absar M, Hasanato RM, Basit S, Chishti MA, Faiyaz Ul-Haque M, Khalid AM, Sabar MF, Rasool M, Karim S, Khan M, Samreen B, Akram AM, Siddiqi MH, Shahzadi S, Shahbaz S, Ali AS, Mahmood A, Akram M, Saeed T, Saleem A, Mohsin D, Shah IH, Khalid M, Asif M, Iqbal M, Akhtar T. Sabir N, et al. Among authors: akram am. Asian Pac J Cancer Prev. 2012;13(7):3349-55. doi: 10.7314/apjcp.2012.13.7.3349. Asian Pac J Cancer Prev. 2012. PMID: 22994759 Free article.
High frequency and poor prognosis of late childhood BCR-ABL-positive and MLL-AF4-positive ALL define the need for advanced molecular diagnostics and improved therapeutic strategies in pediatric B-ALL in Pakistan.
Iqbal Z, Akhtar T, Awan T, Aleem A, Sabir N, Rasool M, Absar M, Akram AM, Shammas MA, Shah IH, Khalid M, Taj AS, Jameel A, Alanazi A, Gill AT, Hashmi JA, Hussain A, Sabar MF, Khalid AM, Qazi MH, Karim S, Siddiqi MH, Mahmood A, Iqbal M, Saeed A, Irfan MI. Iqbal Z, et al. Among authors: akram am. Mol Diagn Ther. 2015 Oct;19(5):277-87. doi: 10.1007/s40291-015-0149-0. Mol Diagn Ther. 2015. PMID: 26266519
Discovery and Protein Modeling Studies of Novel Compound Mutations Causing Resistance to Multiple Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia.
Iqbal Z, Absar M, Mahmood A, Aleem A, Iqbal M, Jameel A, Akhtar T, Karim S, Rasool M, Mirza Z, Khalid M, Akram AM, Sabar MF, Khalid AM, Aljarrah K, Iqbal J, Khalid M, Shah IH, Alanazi N. Iqbal Z, et al. Among authors: akram am. Asian Pac J Cancer Prev. 2020 Dec 1;21(12):3517-3526. doi: 10.31557/APJCP.2020.21.12.3517. Asian Pac J Cancer Prev. 2020. PMID: 33369447 Free PMC article.
RUNX1 mutation and elevated FLT3 gene expression cooperates to induce inferior prognosis in cytogenetically normal acute myeloid leukemia patients.
Rehman A, Akram AM, Chaudhary A, Sheikh N, Hussain Z, Alsanie WF, Rehman RA, Hameed N, Saleem T, Zafar A, Absar M, Iqbal Z, Alhazmi A, Baeshen HA, Mohammedsaleh ZM, Qamer S, Sayed S, Gaber A. Rehman A, et al. Among authors: akram am. Saudi J Biol Sci. 2021 Sep;28(9):4845-4851. doi: 10.1016/j.sjbs.2021.07.012. Epub 2021 Jul 10. Saudi J Biol Sci. 2021. PMID: 34466057 Free PMC article.