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Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent.
Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. Jost M, et al. Among authors: akhmanova a. Mol Cell. 2020 Jul 2;79(1):191-198.e3. doi: 10.1016/j.molcel.2020.06.008. Mol Cell. 2020. PMID: 32619469 Free PMC article.
The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis.
Akhmanova A, Mausset-Bonnefont AL, van Cappellen W, Keijzer N, Hoogenraad CC, Stepanova T, Drabek K, van der Wees J, Mommaas M, Onderwater J, van der Meulen H, Tanenbaum ME, Medema RH, Hoogerbrugge J, Vreeburg J, Uringa EJ, Grootegoed JA, Grosveld F, Galjart N. Akhmanova A, et al. Genes Dev. 2005 Oct 15;19(20):2501-15. doi: 10.1101/gad.344505. Genes Dev. 2005. PMID: 16230537 Free PMC article.
Structure-function relationship of CAP-Gly domains.
Weisbrich A, Honnappa S, Jaussi R, Okhrimenko O, Frey D, Jelesarov I, Akhmanova A, Steinmetz MO. Weisbrich A, et al. Among authors: akhmanova a. Nat Struct Mol Biol. 2007 Oct;14(10):959-67. doi: 10.1038/nsmb1291. Epub 2007 Sep 9. Nat Struct Mol Biol. 2007. PMID: 17828277
STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER.
Grigoriev I, Gouveia SM, van der Vaart B, Demmers J, Smyth JT, Honnappa S, Splinter D, Steinmetz MO, Putney JW Jr, Hoogenraad CC, Akhmanova A. Grigoriev I, et al. Among authors: akhmanova a. Curr Biol. 2008 Feb 12;18(3):177-82. doi: 10.1016/j.cub.2007.12.050. Epub 2008 Jan 31. Curr Biol. 2008. PMID: 18249114 Free PMC article.
Capturing protein tails by CAP-Gly domains.
Steinmetz MO, Akhmanova A. Steinmetz MO, et al. Among authors: akhmanova a. Trends Biochem Sci. 2008 Nov;33(11):535-45. doi: 10.1016/j.tibs.2008.08.006. Epub 2008 Oct 4. Trends Biochem Sci. 2008. PMID: 18835717 Review.
Mammalian end binding proteins control persistent microtubule growth.
Komarova Y, De Groot CO, Grigoriev I, Gouveia SM, Munteanu EL, Schober JM, Honnappa S, Buey RM, Hoogenraad CC, Dogterom M, Borisy GG, Steinmetz MO, Akhmanova A. Komarova Y, et al. Among authors: akhmanova a. J Cell Biol. 2009 Mar 9;184(5):691-706. doi: 10.1083/jcb.200807179. Epub 2009 Mar 2. J Cell Biol. 2009. PMID: 19255245 Free PMC article.
An EB1-binding motif acts as a microtubule tip localization signal.
Honnappa S, Gouveia SM, Weisbrich A, Damberger FF, Bhavesh NS, Jawhari H, Grigoriev I, van Rijssel FJ, Buey RM, Lawera A, Jelesarov I, Winkler FK, Wüthrich K, Akhmanova A, Steinmetz MO. Honnappa S, et al. Among authors: akhmanova a. Cell. 2009 Jul 23;138(2):366-76. doi: 10.1016/j.cell.2009.04.065. Cell. 2009. PMID: 19632184 Free article.
Molecular insights into mammalian end-binding protein heterodimerization.
De Groot CO, Jelesarov I, Damberger FF, Bjelić S, Schärer MA, Bhavesh NS, Grigoriev I, Buey RM, Wüthrich K, Capitani G, Akhmanova A, Steinmetz MO. De Groot CO, et al. Among authors: akhmanova a. J Biol Chem. 2010 Feb 19;285(8):5802-14. doi: 10.1074/jbc.M109.068130. Epub 2009 Dec 12. J Biol Chem. 2010. PMID: 20008324 Free PMC article.
245 results