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Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
Akhlaghpour M, Haritunians T, More SK, Thomas LS, Stamps DT, Dube S, Li D, Yang S, Landers CJ, Mengesha E, Hamade H, Murali R, Potdar AA, Wolf AJ, Botwin GJ, Khrom M; International IBD Genetics Consortium; Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Sartor RB, Xavier RJ, Brant SR, Cho JH, Duerr RH, Lazarev MG, Rioux JD, Schumm LP, Silverberg MS, Zaghiyan K, Fleshner P, Melmed GY, Vasiliauskas EA, Ha C, Rabizadeh S, Syal G, Bonthala NN, Ziring DA, Targan SR, Long MD, McGovern DPB, Michelsen KS. Akhlaghpour M, et al. Gut. 2023 Nov;72(11):2068-2080. doi: 10.1136/gutjnl-2023-329689. Epub 2023 Apr 20. Gut. 2023. PMID: 37080587 Free article.
Mode of conception does not appear to affect placental volume in the first trimester.
Churchill SJ, Wang ET, Akhlaghpour M, Goldstein EH, Eschevarria D, Greene N, Macer M, Zore T, Williams J 3rd, Pisarska MD. Churchill SJ, et al. Among authors: akhlaghpour m. Fertil Steril. 2017 Jun;107(6):1341-1347.e1. doi: 10.1016/j.fertnstert.2017.04.010. Epub 2017 May 10. Fertil Steril. 2017. PMID: 28501362 Free PMC article.
Comparison of Genome-Wide and Gene-Specific DNA Methylation Profiling in First-Trimester Chorionic Villi From Pregnancies Conceived With Infertility Treatments.
Xu N, Barlow GM, Cui J, Wang ET, Lee B, Akhlaghpour M, Kroener L, Williams J 3rd, Rotter JI, Chen YI, Goodarzi MO, Pisarska MD. Xu N, et al. Among authors: akhlaghpour m. Reprod Sci. 2017 Jul;24(7):996-1004. doi: 10.1177/1933719116675056. Epub 2016 Nov 14. Reprod Sci. 2017. PMID: 28090815 Free PMC article.
Optimization of techniques for multiple platform testing in small, precious samples such as human chorionic villus sampling.
Pisarska MD, Akhlaghpour M, Lee B, Barlow GM, Xu N, Wang ET, Mackey AJ, Farber CR, Rich SS, Rotter JI, Chen YI, Goodarzi MO, Guller S, Williams J 3rd. Pisarska MD, et al. Among authors: akhlaghpour m. Prenat Diagn. 2016 Nov;36(11):1061-1070. doi: 10.1002/pd.4936. Epub 2016 Nov 7. Prenat Diagn. 2016. PMID: 27718505 Free PMC article.