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Telaglenastat plus Everolimus in Advanced Renal Cell Carcinoma: A Randomized, Double-Blinded, Placebo-Controlled, Phase II ENTRATA Trial.
Lee CH, Motzer R, Emamekhoo H, Matrana M, Percent I, Hsieh JJ, Hussain A, Vaishampayan U, Liu S, McCune S, Patel V, Shaheen M, Bendell J, Fan AC, Gartrell BA, Goodman OB, Nikolinakos PG, Kalebasty AR, Zakharia Y, Zhang Z, Parmar H, Akella L, Orford K, Tannir NM. Lee CH, et al. Among authors: akella l. Clin Cancer Res. 2022 Aug 2;28(15):3248-3255. doi: 10.1158/1078-0432.CCR-22-0061. Clin Cancer Res. 2022. PMID: 35576438 Free PMC article. Clinical Trial.
Efficacy and Safety of Telaglenastat Plus Cabozantinib vs Placebo Plus Cabozantinib in Patients With Advanced Renal Cell Carcinoma: The CANTATA Randomized Clinical Trial.
Tannir NM, Agarwal N, Porta C, Lawrence NJ, Motzer R, McGregor B, Lee RJ, Jain RK, Davis N, Appleman LJ, Goodman O Jr, Stadler WM, Gandhi S, Geynisman DM, Iacovelli R, Mellado B, Sepúlveda Sánchez JM, Figlin R, Powles T, Akella L, Orford K, Escudier B. Tannir NM, et al. Among authors: akella l. JAMA Oncol. 2022 Oct 1;8(10):1411-1418. doi: 10.1001/jamaoncol.2022.3511. JAMA Oncol. 2022. PMID: 36048457 Free PMC article.
Immunogenicity of a two-dose investigational hepatitis B vaccine, HBsAg-1018, using a toll-like receptor 9 agonist adjuvant compared with a licensed hepatitis B vaccine in adults.
Jackson S, Lentino J, Kopp J, Murray L, Ellison W, Rhee M, Shockey G, Akella L, Erby K, Heyward WL, Janssen RS; HBV-23 Study Group. Jackson S, et al. Among authors: akella l. Vaccine. 2018 Jan 29;36(5):668-674. doi: 10.1016/j.vaccine.2017.12.038. Epub 2017 Dec 27. Vaccine. 2018. PMID: 29289383 Free article. Clinical Trial.
Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides.
Gerard B, Lee MD 4th, Dandapani S, Duvall JR, Fitzgerald ME, Kesavan S, Lowe JT, Marié JC, Pandya BA, Suh BC, O'Shea MW, Dombrowski M, Hamann D, Lemercier B, Murillo T, Akella LB, Foley MA, Marcaurelle LA. Gerard B, et al. Among authors: akella lb. J Org Chem. 2013 Jun 7;78(11):5160-71. doi: 10.1021/jo4000916. Epub 2013 May 21. J Org Chem. 2013. PMID: 23692141 Free PMC article.
An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries.
Mulrooney CA, Lahr DL, Quintin MJ, Youngsaye W, Moccia D, Asiedu JK, Mulligan EL, Akella LB, Marcaurelle LA, Montgomery P, Bittker JA, Clemons PA, Brudz S, Dandapani S, Duvall JR, Tolliday NJ, De Souza A. Mulrooney CA, et al. Among authors: akella lb. J Comput Aided Mol Des. 2013 May;27(5):455-68. doi: 10.1007/s10822-013-9641-y. Epub 2013 Apr 13. J Comput Aided Mol Des. 2013. PMID: 23585218 Free PMC article.
Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.
Lowe JT, Lee MD 4th, Akella LB, Davoine E, Donckele EJ, Durak L, Duvall JR, Gerard B, Holson EB, Joliton A, Kesavan S, Lemercier BC, Liu H, Marié JC, Mulrooney CA, Muncipinto G, Welzel-O'Shea M, Panko LM, Rowley A, Suh BC, Thomas M, Wagner FF, Wei J, Foley MA, Marcaurelle LA. Lowe JT, et al. Among authors: akella lb. J Org Chem. 2012 Sep 7;77(17):7187-211. doi: 10.1021/jo300974j. Epub 2012 Aug 10. J Org Chem. 2012. PMID: 22853001 Free PMC article.
20 results