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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2006 2
2007 4
2008 13
2009 11
2010 24
2011 11
2012 12
2013 21
2014 22
2015 11
2016 17
2017 12
2018 19
2019 8
2020 11
2021 8
2022 5
2024 0

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175 results

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Page 1
A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2.
Scoles DR, Gandelman M, Paul S, Dexheimer T, Dansithong W, Figueroa KP, Pflieger LT, Redlin S, Kales SC, Sun H, Maloney D, Damoiseaux R, Henderson MJ, Simeonov A, Jadhav A, Pulst SM. Scoles DR, et al. Among authors: jadhav a. J Biol Chem. 2022 Aug;298(8):102228. doi: 10.1016/j.jbc.2022.102228. Epub 2022 Jul 2. J Biol Chem. 2022. PMID: 35787375 Free PMC article.
Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis.
Frankowski KJ, Patnaik S, Wang C, Southall N, Dutta D, De S, Li D, Dextras C, Lin YH, Bryant-Connah M, Davis D, Wang F, Wachsmuth LM, Shah P, Williams J, Kabir M, Zhu E, Baljinnyam B, Wang A, Xu X, Norton J, Ferrer M, Titus S, Simeonov A, Zheng W, Mathews Griner LA, Jadhav A, Aubé J, Henderson MJ, Rudloff U, Schoenen FJ, Huang S, Marugan JJ. Frankowski KJ, et al. Among authors: jadhav a. J Med Chem. 2022 Jun 23;65(12):8303-8331. doi: 10.1021/acs.jmedchem.2c00204. Epub 2022 Jun 13. J Med Chem. 2022. PMID: 35696646 Free PMC article.
NCATS Inxight Drugs: a comprehensive and curated portal for translational research.
Siramshetty VB, Grishagin I, Nguyễn ÐT, Peryea T, Skovpen Y, Stroganov O, Katzel D, Sheils T, Jadhav A, Mathé EA, Southall NT. Siramshetty VB, et al. Among authors: jadhav a. Nucleic Acids Res. 2022 Jan 7;50(D1):D1307-D1316. doi: 10.1093/nar/gkab918. Nucleic Acids Res. 2022. PMID: 34648031 Free PMC article.
The AKT modulator A-443654 reduces α-synuclein expression and normalizes ER stress and autophagy.
Gandelman M, Dansithong W, Kales SC, Paul S, Maag G, Aoyama E, Zakharov A, Rai G, Dexheimer T, Whitehill BM, Sun H, Jadhav A, Simeonov A, Henderson MJ, Huynh DP, Pulst SM, Scoles DR. Gandelman M, et al. Among authors: jadhav a. J Biol Chem. 2021 Oct;297(4):101191. doi: 10.1016/j.jbc.2021.101191. Epub 2021 Sep 11. J Biol Chem. 2021. PMID: 34520759 Free PMC article.
Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2.
Tsai WC, Gilbert NC, Ohler A, Armstrong M, Perry S, Kalyanaraman C, Yasgar A, Rai G, Simeonov A, Jadhav A, Standley M, Lee HW, Crews P, Iavarone AT, Jacobson MP, Neau DB, Offenbacher AR, Newcomer M, Holman TR. Tsai WC, et al. Among authors: jadhav a. Bioorg Med Chem. 2021 Sep 15;46:116349. doi: 10.1016/j.bmc.2021.116349. Epub 2021 Aug 5. Bioorg Med Chem. 2021. PMID: 34500187 Free PMC article.
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Henderson MJ, Trychta KA, Yang SM, Bäck S, Yasgar A, Wires ES, Danchik C, Yan X, Yano H, Shi L, Wu KJ, Wang AQ, Tao D, Zahoránszky-Kőhalmi G, Hu X, Xu X, Maloney D, Zakharov AV, Rai G, Urano F, Airavaara M, Gavrilova O, Jadhav A, Wang Y, Simeonov A, Harvey BK. Henderson MJ, et al. Among authors: jadhav a. Cell Rep. 2021 Apr 27;35(4):109040. doi: 10.1016/j.celrep.2021.109040. Cell Rep. 2021. PMID: 33910017 Free PMC article.
175 results