Aitkenhead H - Search Results

1

Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair.

Vaz B, Popovic M, Newman JA, Fielden J, Aitkenhead H, Halder S, Singh AN, Vendrell I, Fischer R, Torrecilla I, Drobnitzky N, Freire R, Amor DJ, Lockhart PJ, Kessler BM, McKenna GW, Gileadi O, Ramadan K. Vaz B, et al. Among authors: aitkenhead h. Mol Cell. 2016 Nov 17;64(4):704-719. doi: 10.1016/j.molcel.2016.09.032. Epub 2016 Oct 27. Mol Cell. 2016. PMID: 27871366 Free PMC article.

2

Structural insights into the autoregulation and cooperativity of the human transcription factor Ets-2.

Newman JA, Cooper CD, Aitkenhead H, Gileadi O. Newman JA, et al. Among authors: aitkenhead h. J Biol Chem. 2015 Mar 27;290(13):8539-49. doi: 10.1074/jbc.M114.619270. Epub 2015 Feb 10. J Biol Chem. 2015. PMID: 25670864 Free PMC article.

3

Structures of the Ets Protein DNA-binding Domains of Transcription Factors Etv1, Etv4, Etv5, and Fev: DETERMINANTS OF DNA BINDING AND REDOX REGULATION BY DISULFIDE BOND FORMATION.

Cooper CD, Newman JA, Aitkenhead H, Allerston CK, Gileadi O. Cooper CD, et al. Among authors: aitkenhead h. J Biol Chem. 2015 May 29;290(22):13692-709. doi: 10.1074/jbc.M115.646737. Epub 2015 Apr 12. J Biol Chem. 2015. PMID: 25866208 Free PMC article.

4

Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.

Newman JA, Cooper CDO, Aitkenhead H, Gileadi O. Newman JA, et al. Among authors: aitkenhead h. Structure. 2015 Dec 1;23(12):2319-2330. doi: 10.1016/j.str.2015.10.014. Structure. 2015. PMID: 26636256 Free PMC article.

5

Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.

Newman JA, Aitkenhead H, Savitsky P, Gileadi O. Newman JA, et al. Among authors: aitkenhead h. Nucleic Acids Res. 2017 Apr 20;45(7):4231-4243. doi: 10.1093/nar/gkw1362. Nucleic Acids Res. 2017. PMID: 28100692 Free PMC article.

6

The crystal structure of human forkhead box N1 in complex with DNA reveals the structural basis for forkhead box family specificity.

Newman JA, Aitkenhead H, Gavard AE, Rota IA, Handel AE, Hollander GA, Gileadi O. Newman JA, et al. Among authors: aitkenhead h. J Biol Chem. 2020 Mar 6;295(10):2948-2958. doi: 10.1074/jbc.RA119.010365. Epub 2019 Dec 30. J Biol Chem. 2020. PMID: 31914405 Free PMC article.

7

Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding.

Newman JA, Cooper CD, Roos AK, Aitkenhead H, Oppermann UC, Cho HJ, Osman R, Gileadi O. Newman JA, et al. Among authors: aitkenhead h. PLoS One. 2016 Feb 24;11(2):e0148762. doi: 10.1371/journal.pone.0148762. eCollection 2016. PLoS One. 2016. PMID: 26910052 Free PMC article.

8

A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin.

Lim M, Newman JA, Williams HL, Masino L, Aitkenhead H, Gravard AE, Gileadi O, Svejstrup JQ. Lim M, et al. Among authors: aitkenhead h. Structure. 2019 Aug 6;27(8):1316-1325.e6. doi: 10.1016/j.str.2019.05.003. Epub 2019 Jun 13. Structure. 2019. PMID: 31204252 Free PMC article.

9

Activation of a primed RING E3-E2-ubiquitin complex by non-covalent ubiquitin.

Buetow L, Gabrielsen M, Anthony NG, Dou H, Patel A, Aitkenhead H, Sibbet GJ, Smith BO, Huang DT. Buetow L, et al. Among authors: aitkenhead h. Mol Cell. 2015 Apr 16;58(2):297-310. doi: 10.1016/j.molcel.2015.02.017. Epub 2015 Mar 19. Mol Cell. 2015. PMID: 25801170 Free article.

10

Incidental Detection of Classical Galactosemia through Newborn Screening for Phenylketonuria: A 10-Year Retrospective Audit to Determine the Efficacy of This Approach.

Cantley NWP, Barski R, Kemp H, Hogg SL, Wu HYT, Bowron A, Collingwood C, Cundick J, Hart C, Shakespeare L, Preece MA, Aitkenhead H, Smith S, Carling RS, Moat SJ. Cantley NWP, et al. Among authors: aitkenhead h. Int J Neonatal Screen. 2023 Dec 22;10(1):2. doi: 10.3390/ijns10010002. Int J Neonatal Screen. 2023. PMID: 38248630 Free PMC article.

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