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PI3K Inhibitors Curtail MYC-Dependent Mutant p53 Gain-of-Function in Head and Neck Squamous Cell Carcinoma.
Ganci F, Pulito C, Valsoni S, Sacconi A, Turco C, Vahabi M, Manciocco V, Mazza EMC, Meens J, Karamboulas C, Nichols AC, Covello R, Pellini R, Spriano G, Sanguineti G, Muti P, Bicciato S, Ailles L, Strano S, Fontemaggi G, Blandino G. Ganci F, et al. Among authors: ailles l. Clin Cancer Res. 2020 Jun 15;26(12):2956-2971. doi: 10.1158/1078-0432.CCR-19-2485. Epub 2020 Jan 22. Clin Cancer Res. 2020. PMID: 31969334
TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma.
Ruicci KM, Meens J, Plantinga P, Stecho W, Pinto N, Yoo J, Fung K, MacNeil D, Mymryk JS, Barrett JW, Howlett CJ, Boutros PC, Ailles L, Nichols AC. Ruicci KM, et al. Among authors: ailles l. J Exp Clin Cancer Res. 2020 Oct 15;39(1):217. doi: 10.1186/s13046-020-01713-9. J Exp Clin Cancer Res. 2020. PMID: 33059733 Free PMC article.
Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma.
Karamboulas C, Bruce JP, Hope AJ, Meens J, Huang SH, Erdmann N, Hyatt E, Pereira K, Goldstein DP, Weinreb I, Su J, O'Sullivan B, Tiedemann R, Liu FF, Pugh TJ, Bratman SV, Xu W, Ailles L. Karamboulas C, et al. Among authors: ailles l. Cell Rep. 2018 Oct 30;25(5):1318-1331.e4. doi: 10.1016/j.celrep.2018.10.004. Cell Rep. 2018. PMID: 30380421 Free article.
Spleen tyrosine kinase expression is correlated with human papillomavirus in head and neck cancer.
Black M, Ghasemi F, Sun RX, Stecho W, Datti A, Meens J, Pinto N, Ruicci KM, Khan MI, Han MW, Shaikh M, Yoo J, Fung K, MacNeil D, Palma DA, Winquist E, Howlett CJ, Mymryk JS, Ailles L, Boutros PC, Barrett JW, Nichols AC. Black M, et al. Among authors: ailles l. Oral Oncol. 2020 Feb;101:104529. doi: 10.1016/j.oraloncology.2019.104529. Epub 2019 Dec 19. Oral Oncol. 2020. PMID: 31864959
Flavopiridol causes cell cycle inhibition and demonstrates anti-cancer activity in anaplastic thyroid cancer models.
Pinto N, Prokopec SD, Ghasemi F, Meens J, Ruicci KM, Khan IM, Mundi N, Patel K, Han MW, Yoo J, Fung K, MacNeil D, Mymryk JS, Datti A, Barrett JW, Boutros PC, Ailles L, Nichols AC. Pinto N, et al. Among authors: ailles l. PLoS One. 2020 Sep 24;15(9):e0239315. doi: 10.1371/journal.pone.0239315. eCollection 2020. PLoS One. 2020. PMID: 32970704 Free PMC article.
Development and Validation of an Oral Cavity Cancer Outcomes Prediction Score Incorporating Patient-Derived Xenograft Engraftment.
Id Said B, Ailles L, Karamboulas C, Meens J, Huang SH, Xu W, Keshavarzi S, Bratman SV, Cho BCJ, Giuliani M, Hahn E, Kim J, O'Sullivan B, Ringash J, Waldron J, Spreafico A, de Almeida JR, Chepeha DB, Irish JC, Goldstein DP, Hope A, Hosni A. Id Said B, et al. Among authors: ailles l. JAMA Otolaryngol Head Neck Surg. 2022 Apr 1;148(4):342-349. doi: 10.1001/jamaoto.2022.0003. JAMA Otolaryngol Head Neck Surg. 2022. PMID: 35238880 Free PMC article.
93 results