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One-step rapid tracking and isolation of senescent cells in cellular systems, tissues, or animal models via GLF16.
Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Giannetti K, Pippa N, Lougiakis N, Kambas K, Lagopati N, Polyzou A, Georgiou M, Chountoulesi M, Pispas S, Foutadakis S, Kyrodimos E, Pouli N, Marakos P, Kotsinas A, Verginis P, Valakos D, Vatsellas G, Petty R, Thanos D, Demaria M, Evangelou K, Di Micco R, Gorgoulis VG. Magkouta S, et al. Among authors: polyzou a. STAR Protoc. 2024 Mar 15;5(1):102929. doi: 10.1016/j.xpro.2024.102929. Epub 2024 Mar 8. STAR Protoc. 2024. PMID: 38460134 Free PMC article.
Senescent cells in giant cell arteritis display an inflammatory phenotype participating in tissue injury via IL-6-dependent pathways.
Veroutis D, Argyropoulou OD, Goules AV, Kambas K, Palamidas DA, Evangelou K, Havaki S, Polyzou A, Valakos D, Xingi E, Karatza E, Boki KA, Cavazza A, Kittas C, Thanos D, Ricordi C, Marvisi C, Muratore F, Galli E, Croci S, Salvarani C, Gorgoulis VG, Tzioufas AG. Veroutis D, et al. Among authors: polyzou a. Ann Rheum Dis. 2024 Feb 15;83(3):342-350. doi: 10.1136/ard-2023-224467. Ann Rheum Dis. 2024. PMID: 38050005
A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells.
Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Pippa N, Lougiakis N, Kambas K, Lagopati N, Polyzou A, Georgiou M, Chountoulesi M, Pispas S, Foutadakis S, Pouli N, Marakos P, Kotsinas A, Verginis P, Valakos D, Mizi A, Papantonis A, Vatsellas G, Galanos P, Bartek J, Petty R, Serrano M, Thanos D, Roussos C, Demaria M, Evangelou K, Gorgoulis VG. Magkouta S, et al. Among authors: polyzou a. Mol Cell. 2023 Oct 5;83(19):3558-3573.e7. doi: 10.1016/j.molcel.2023.09.006. Mol Cell. 2023. PMID: 37802028
A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancer.
Mourkioti I, Polyzou A, Veroutis D, Theocharous G, Lagopati N, Gentile E, Stravokefalou V, Thanos DF, Havaki S, Kletsas D, Panaretakis T, Logothetis CJ, Stellas D, Petty R, Blandino G, Papaspyropoulos A, Gorgoulis VG. Mourkioti I, et al. Among authors: polyzou a. J Exp Clin Cancer Res. 2023 Jul 29;42(1):187. doi: 10.1186/s13046-023-02769-z. J Exp Clin Cancer Res. 2023. PMID: 37507762 Free PMC article.
TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages.
Schuster EM, Epple MW, Glaser KM, Mihlan M, Lucht K, Zimmermann JA, Bremser A, Polyzou A, Obier N, Cabezas-Wallscheid N, Trompouki E, Ballabio A, Vogel J, Buescher JM, Westermann AJ, Rambold AS. Schuster EM, et al. Among authors: polyzou a. Nat Metab. 2022 Jul;4(7):856-866. doi: 10.1038/s42255-022-00605-w. Epub 2022 Jul 21. Nat Metab. 2022. PMID: 35864246 Free PMC article.
Pulmonary infection by SARS-CoV-2 induces senescence accompanied by an inflammatory phenotype in severe COVID-19: possible implications for viral mutagenesis.
Evangelou K, Veroutis D, Paschalaki K, Foukas PG, Lagopati N, Dimitriou M, Papaspyropoulos A, Konda B, Hazapis O, Polyzou A, Havaki S, Kotsinas A, Kittas C, Tzioufas AG, de Leval L, Vassilakos D, Tsiodras S, Stripp BR, Papantonis A, Blandino G, Karakasiliotis I, Barnes PJ, Gorgoulis VG. Evangelou K, et al. Among authors: polyzou a. Eur Respir J. 2022 Aug 18;60(2):2102951. doi: 10.1183/13993003.02951-2021. Print 2022 Aug. Eur Respir J. 2022. PMID: 35086840 Free PMC article.
RASSF1A disrupts the NOTCH signaling axis via SNURF/RNF4-mediated ubiquitination of HES1.
Papaspyropoulos A, Angelopoulou A, Mourkioti I, Polyzou A, Pankova D, Toskas K, Lanfredini S, Pantazaki AA, Lagopati N, Kotsinas A, Evangelou K, Chronopoulos E, O'Neill E, Gorgoulis V. Papaspyropoulos A, et al. Among authors: polyzou a. EMBO Rep. 2022 Feb 3;23(2):e51287. doi: 10.15252/embr.202051287. Epub 2021 Dec 13. EMBO Rep. 2022. PMID: 34897944 Free PMC article.
Corrigendum to "Evaluation of senescent cells in intervertebral discs by lipofuscin staining" [Mech. Ageing Dev. 199 (2021) 1-9/111564].
Veroutis D, Kouroumalis A, Lagopati N, Polyzou A, Chamilos C, Papadodima S, Evangelou K, Gorgoulis VG, Kletsas D. Veroutis D, et al. Among authors: polyzou a. Mech Ageing Dev. 2022 Jan;201:111603. doi: 10.1016/j.mad.2021.111603. Epub 2021 Nov 18. Mech Ageing Dev. 2022. PMID: 34801260 Free article. No abstract available.
19 results