Ai M - Search Results

1

GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist-Induced Nausea and Emesis in Preclinical Models.

Borner T, Geisler CE, Fortin SM, Cosgrove R, Alsina-Fernandez J, Dogra M, Doebley S, Sanchez-Navarro MJ, Leon RM, Gaisinsky J, White A, Bamezai A, Ghidewon MY, Grill HJ, Crist RC, Reiner BC, Ai M, Samms RJ, De Jonghe BC, Hayes MR. Borner T, et al. Among authors: ai m. Diabetes. 2021 Nov;70(11):2545-2553. doi: 10.2337/db21-0459. Epub 2021 Aug 11. Diabetes. 2021. PMID: 34380697 Free PMC article.

2

GIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior.

Samms RJ, Cosgrove R, Snider BM, Furber EC, Droz BA, Briere DA, Dunbar J, Dogra M, Alsina-Fernandez J, Borner T, De Jonghe BC, Hayes MR, Coskun T, Sloop KW, Emmerson PJ, Ai M. Samms RJ, et al. Among authors: ai m. Diabetes. 2022 Jul 1;71(7):1410-1423. doi: 10.2337/db21-0848. Diabetes. 2022. PMID: 35499381 Free PMC article.

3

Anorectic and aversive effects of GLP-1 receptor agonism are mediated by brainstem cholecystokinin neurons, and modulated by GIP receptor activation.

Costa A, Ai M, Nunn N, Culotta I, Hunter J, Boudjadja MB, Valencia-Torres L, Aviello G, Hodson DJ, Snider BM, Coskun T, Emmerson PJ, Luckman SM, D'Agostino G. Costa A, et al. Among authors: ai m. Mol Metab. 2022 Jan;55:101407. doi: 10.1016/j.molmet.2021.101407. Epub 2021 Nov 26. Mol Metab. 2022. PMID: 34844019 Free PMC article.

4

Long-Acting and Selective Oxytocin Peptide Analogs Show Antidiabetic and Antiobesity Effects in Male Mice.

Snider B, Geiser A, Yu XP, Beebe EC, Willency JA, Qing K, Guo L, Lu J, Wang X, Yang Q, Efanov A, Adams AC, Coskun T, Emmerson PJ, Alsina-Fernandez J, Ai M. Snider B, et al. Among authors: ai m. J Endocr Soc. 2019 May 16;3(7):1423-1444. doi: 10.1210/js.2019-00004. eCollection 2019 Jul 1. J Endocr Soc. 2019. PMID: 31286109 Free PMC article.

5

The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment.

Sawakami K, Robling AG, Ai M, Pitner ND, Liu D, Warden SJ, Li J, Maye P, Rowe DW, Duncan RL, Warman ML, Turner CH. Sawakami K, et al. Among authors: ai m. J Biol Chem. 2006 Aug 18;281(33):23698-711. doi: 10.1074/jbc.M601000200. Epub 2006 Jun 20. J Biol Chem. 2006. PMID: 16790443 Free article.

6

Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling.

Ai M, Holmen SL, Van Hul W, Williams BO, Warman ML. Ai M, et al. Mol Cell Biol. 2005 Jun;25(12):4946-55. doi: 10.1128/MCB.25.12.4946-4955.2005. Mol Cell Biol. 2005. PMID: 15923613 Free PMC article.

7

Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice.

Clément-Lacroix P, Ai M, Morvan F, Roman-Roman S, Vayssière B, Belleville C, Estrera K, Warman ML, Baron R, Rawadi G. Clément-Lacroix P, et al. Among authors: ai m. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17406-11. doi: 10.1073/pnas.0505259102. Epub 2005 Nov 17. Proc Natl Acad Sci U S A. 2005. PMID: 16293698 Free PMC article.

8

The binding between sclerostin and LRP5 is altered by DKK1 and by high-bone mass LRP5 mutations.

Balemans W, Piters E, Cleiren E, Ai M, Van Wesenbeeck L, Warman ML, Van Hul W. Balemans W, et al. Among authors: ai m. Calcif Tissue Int. 2008 Jun;82(6):445-53. doi: 10.1007/s00223-008-9130-9. Calcif Tissue Int. 2008. PMID: 18521528

9

Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.

Holmen SL, Giambernardi TA, Zylstra CR, Buckner-Berghuis BD, Resau JH, Hess JF, Glatt V, Bouxsein ML, Ai M, Warman ML, Williams BO. Holmen SL, et al. Among authors: ai m. J Bone Miner Res. 2004 Dec;19(12):2033-40. doi: 10.1359/JBMR.040907. Epub 2004 Sep 13. J Bone Miner Res. 2004. PMID: 15537447 Free article.

10

A mutation in the signal sequence of LRP5 in a family with an osteoporosis-pseudoglioma syndrome (OPPG)-like phenotype indicates a novel disease mechanism for trinucleotide repeats.

Chung BD, Kayserili H, Ai M, Freudenberg J, Uzümcü A, Uyguner O, Bartels CF, Höning S, Ramirez A, Hanisch FG, Nürnberg G, Nürnberg P, Warman ML, Wollnik B, Kubisch C, Netzer C. Chung BD, et al. Among authors: ai m. Hum Mutat. 2009 Apr;30(4):641-8. doi: 10.1002/humu.20916. Hum Mutat. 2009. PMID: 19177549

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