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Ursolic acid facilitates apoptosis in rheumatoid arthritis synovial fibroblasts by inducing SP1-mediated Noxa expression and proteasomal degradation of Mcl-1.
Kim EY, Sudini K, Singh AK, Haque M, Leaman D, Khuder S, Ahmed S. Kim EY, et al. Among authors: ahmed s. FASEB J. 2018 May 25;32(11):fj201800425R. doi: 10.1096/fj.201800425R. Online ahead of print. FASEB J. 2018. PMID: 29799788 Free PMC article.
-Kim, E. Y., Sudini, K., Singh, A. K., Haque, M., Leaman, D., Khuder, S., Ahmed, S. Ursolic acid facilitates apoptosis in rheumatoid arthritis synovial fibroblasts by inducing SP1-mediated Noxa expression and proteasomal degradation of Mcl-1....
-Kim, E. Y., Sudini, K., Singh, A. K., Haque, M., Leaman, D., Khuder, S., Ahmed, S. Ursolic acid facilitates apoptosis …
Critical role of IL-1α in IL-1β-induced inflammatory responses: cooperation with NF-κBp65 in transcriptional regulation.
Singh AK, Fechtner S, Chourasia M, Sicalo J, Ahmed S. Singh AK, et al. Among authors: ahmed s. FASEB J. 2019 Feb;33(2):2526-2536. doi: 10.1096/fj.201801513R. Epub 2018 Oct 1. FASEB J. 2019. PMID: 30272996 Free PMC article.
Our study highlights the importance of IL-1alpha in mediating IL-1beta-induced inflammation in addition to maintaining its expression and providing a rationale for targeting IL-1alpha to minimize the role of IL-1beta in inflammatory diseases like RA.-Singh, A. K., Fechtner, S …
Our study highlights the importance of IL-1alpha in mediating IL-1beta-induced inflammation in addition to maintaining its expression and pr …
Noxa in rheumatic diseases: present understanding and future impact.
Cottier KE, Fogle EM, Fox DA, Ahmed S. Cottier KE, et al. Among authors: ahmed s. Rheumatology (Oxford). 2014 Sep;53(9):1539-46. doi: 10.1093/rheumatology/ket408. Epub 2013 Dec 17. Rheumatology (Oxford). 2014. PMID: 24352336 Free PMC article. Review.
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