Ahmed M. El Kerdawy - Search Results

Year	Number of Results
2010	1
2016	1
2017	2
2018	3
2019	6
2020	11
2021	7
2022	12
2023	7
2024	9

1

Discovery of novel quinolin-2-one derivatives as potential GSK-3β inhibitors for treatment of Alzheimer's disease: Pharmacophore-based design, preliminary SAR, in vitro and in vivo biological evaluation.

Abdo Moustafa E, Abdelrasheed Allam H, Fouad MA, El Kerdawy AM, Nasser Eid El-Sayed N, Wagner C, Abdel-Aziz HA, Abdel Fattah Ezzat M. Abdo Moustafa E, et al. Among authors: el kerdawy am. Bioorg Chem. 2024 May;146:107324. doi: 10.1016/j.bioorg.2024.107324. Epub 2024 Mar 30. Bioorg Chem. 2024. PMID: 38569322

2

In Silico and In Vitro Screening of Some Pregnane Glycosides Isolated from Certain Caralluma Species as SARS-COV-2 Main Protease Inhibitors.

Abdel-Sattar E, Kutkat O, El-Shiekh RA, El-Ashrey MK, El Kerdawy AM. Abdel-Sattar E, et al. Among authors: el kerdawy am. Chem Biodivers. 2024 Apr;21(4):e202301786. doi: 10.1002/cbdv.202301786. Epub 2024 Mar 11. Chem Biodivers. 2024. PMID: 38466126

3

Novel thiazolidin-4-one benzenesulfonamide hybrids as PPARγ agonists: Design, synthesis and in vivo anti-diabetic evaluation.

Ali IH, Hassan RM, El Kerdawy AM, Abo-Elfadl MT, Abdallah HMI, Sciandra F, Ghannam IAY. Ali IH, et al. Among authors: el kerdawy am. Eur J Med Chem. 2024 Apr 5;269:116279. doi: 10.1016/j.ejmech.2024.116279. Epub 2024 Feb 29. Eur J Med Chem. 2024. PMID: 38460271

4

Benzimidazole-oxindole hybrids as multi-kinase inhibitors targeting melanoma.

Allam RM, El Kerdawy AM, Gouda AE, Ahmed KA, Abdel-Mohsen HT. Allam RM, et al. Among authors: el kerdawy am. Bioorg Chem. 2024 May;146:107243. doi: 10.1016/j.bioorg.2024.107243. Epub 2024 Feb 26. Bioorg Chem. 2024. PMID: 38457953

5

Receptor-based pharmacophore modeling, molecular docking, synthesis and biological evaluation of novel VEGFR-2, FGFR-1, and BRAF multi-kinase inhibitors.

Abdel-Mohsen HT, Ibrahim MA, Nageeb AM, El Kerdawy AM. Abdel-Mohsen HT, et al. Among authors: el kerdawy am. BMC Chem. 2024 Feb 23;18(1):42. doi: 10.1186/s13065-024-01135-0. BMC Chem. 2024. PMID: 38395926 Free PMC article.

6

Discovery of dual kinase inhibitors targeting VEGFR2 and FAK: structure-based pharmacophore modeling, virtual screening, and molecular docking studies.

Fouad MA, Osman AA, Abdelhamid NM, Rashad MW, Nabawy AY, El Kerdawy AM. Fouad MA, et al. Among authors: el kerdawy am. BMC Chem. 2024 Feb 12;18(1):29. doi: 10.1186/s13065-024-01130-5. BMC Chem. 2024. PMID: 38347617 Free PMC article.

7

Discovery of dual rho-associated protein kinase 1 (ROCK1)/apoptosis signal-regulating kinase 1 (ASK1) inhibitors as a novel approach for non-alcoholic steatohepatitis (NASH) treatment.

Zaky YA, Rashad MW, Zaater MA, El Kerdawy AM. Zaky YA, et al. Among authors: el kerdawy am. BMC Chem. 2024 Jan 3;18(1):2. doi: 10.1186/s13065-023-01081-3. BMC Chem. 2024. PMID: 38172941 Free PMC article.

8

Morin suppresses mTORc1/IRE-1α/JNK and IP3R-VDAC-1 pathways: Crucial mechanisms in apoptosis and mitophagy inhibition in experimental Huntington's disease, supported by in silico molecular docking simulations.

El-Emam MA, Sheta E, El-Abhar HS, Abdallah DM, El Kerdawy AM, Eldehna WM, Gowayed MA. El-Emam MA, et al. Among authors: el kerdawy am. Life Sci. 2024 Feb 1;338:122362. doi: 10.1016/j.lfs.2023.122362. Epub 2023 Dec 21. Life Sci. 2024. PMID: 38141855

9

Rational design and synthesis of novel quinazolinone N-acetohydrazides as type II multi-kinase inhibitors and potential anticancer agents.

Abd El-Karim SS, Syam YM, El Kerdawy AM, Abdel-Mohsen HT. Abd El-Karim SS, et al. Among authors: el kerdawy am. Bioorg Chem. 2024 Jan;142:106920. doi: 10.1016/j.bioorg.2023.106920. Epub 2023 Oct 18. Bioorg Chem. 2024. PMID: 37898082

10

Discovery of a new potent oxindole multi-kinase inhibitor among a series of designed 3-alkenyl-oxindoles with ancillary carbonic anhydrase inhibitory activity as antiproliferative agents.

Ismail RSM, El Kerdawy AM, Soliman DH, Georgey HH, Abdel Gawad NM, Angeli A, Supuran CT. Ismail RSM, et al. Among authors: el kerdawy am. BMC Chem. 2023 Jul 18;17(1):81. doi: 10.1186/s13065-023-00994-3. BMC Chem. 2023. PMID: 37461110 Free PMC article.

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