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Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia.
Ahmadi S, Bozoky Z, Di Paola M, Xia S, Li C, Wong AP, Wellhauser L, Molinski SV, Ip W, Ouyang H, Avolio J, Forman-Kay JD, Ratjen F, Hirota JA, Rommens J, Rossant J, Gonska T, Moraes TJ, Bear CE. Ahmadi S, et al. NPJ Genom Med. 2017 Apr 14;2:12. doi: 10.1038/s41525-017-0015-6. NPJ Genom Med. 2017. PMID: 28649446 Free PMC article.
Functional Rescue of F508del-CFTR Using Small Molecule Correctors.
Molinski S, Eckford PD, Pasyk S, Ahmadi S, Chin S, Bear CE. Molinski S, et al. Among authors: ahmadi s. Front Pharmacol. 2012 Sep 26;3:160. doi: 10.3389/fphar.2012.00160. eCollection 2012. Front Pharmacol. 2012. PMID: 23055971 Free PMC article.
Synergy of cAMP and calcium signaling pathways in CFTR regulation.
Bozoky Z, Ahmadi S, Milman T, Kim TH, Du K, Di Paola M, Pasyk S, Pekhletski R, Keller JP, Bear CE, Forman-Kay JD. Bozoky Z, et al. Among authors: ahmadi s. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2086-E2095. doi: 10.1073/pnas.1613546114. Epub 2017 Feb 27. Proc Natl Acad Sci U S A. 2017. PMID: 28242698 Free PMC article.
Orkambi® and amplifier co-therapy improves function from a rare CFTR mutation in gene-edited cells and patient tissue.
Molinski SV, Ahmadi S, Ip W, Ouyang H, Villella A, Miller JP, Lee PS, Kulleperuma K, Du K, Di Paola M, Eckford PD, Laselva O, Huan LJ, Wellhauser L, Li E, Ray PN, Pomès R, Moraes TJ, Gonska T, Ratjen F, Bear CE. Molinski SV, et al. Among authors: ahmadi s. EMBO Mol Med. 2017 Sep;9(9):1224-1243. doi: 10.15252/emmm.201607137. EMBO Mol Med. 2017. PMID: 28667089 Free PMC article.
Augmentation of Cystic Fibrosis Transmembrane Conductance Regulator Function in Human Bronchial Epithelial Cells via SLC6A14-Dependent Amino Acid Uptake. Implications for Treatment of Cystic Fibrosis.
Ahmadi S, Wu YS, Li M, Ip W, Lloyd-Kuzik A, Di Paola M, Du K, Xia S, Lew A, Bozoky Z, Forman-Kay J, Bear CE, Gonska T. Ahmadi S, et al. Am J Respir Cell Mol Biol. 2019 Dec;61(6):755-764. doi: 10.1165/rcmb.2019-0094OC. Am J Respir Cell Mol Biol. 2019. PMID: 31189070
ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel.
Wu YS, Jiang J, Ahmadi S, Lew A, Laselva O, Xia S, Bartlett C, Ip W, Wellhauser L, Ouyang H, Gonska T, Moraes TJ, Bear CE. Wu YS, et al. Among authors: ahmadi s. Mol Pharmacol. 2019 Oct;96(4):515-525. doi: 10.1124/mol.119.117143. Epub 2019 Aug 19. Mol Pharmacol. 2019. PMID: 31427400
1,195 results