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The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer.
Folkes AJ, Ahmadi K, Alderton WK, Alix S, Baker SJ, Box G, Chuckowree IS, Clarke PA, Depledge P, Eccles SA, Friedman LS, Hayes A, Hancox TC, Kugendradas A, Lensun L, Moore P, Olivero AG, Pang J, Patel S, Pergl-Wilson GH, Raynaud FI, Robson A, Saghir N, Salphati L, Sohal S, Ultsch MH, Valenti M, Wallweber HJ, Wan NC, Wiesmann C, Workman P, Zhyvoloup A, Zvelebil MJ, Shuttleworth SJ. Folkes AJ, et al. Among authors: ahmadi k. J Med Chem. 2008 Sep 25;51(18):5522-32. doi: 10.1021/jm800295d. J Med Chem. 2008. PMID: 18754654
Synthesis and function of 3-phosphorylated inositol lipids.
Vanhaesebroeck B, Leevers SJ, Ahmadi K, Timms J, Katso R, Driscoll PC, Woscholski R, Parker PJ, Waterfield MD. Vanhaesebroeck B, et al. Among authors: ahmadi k. Annu Rev Biochem. 2001;70:535-602. doi: 10.1146/annurev.biochem.70.1.535. Annu Rev Biochem. 2001. PMID: 11395417 Review.
The Abundance of Plasmid-Mediated Quinolone Resistance Genes in Enterobacter cloacae Strains Isolated from Clinical Specimens in Kermanshah, Iran.
Afsharian M, Asadi S, Danesh C, Sedighi R, Karimi K, Miladi N, Miladi R, Azizi M, Madadi-Goli N, Ahmadi K, Zamanian MH. Afsharian M, et al. Among authors: ahmadi k. Can J Infect Dis Med Microbiol. 2024 Apr 8;2024:8849097. doi: 10.1155/2024/8849097. eCollection 2024. Can J Infect Dis Med Microbiol. 2024. PMID: 38623587 Free PMC article.
417 results