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Envelope protein ubiquitination drives entry and pathogenesis of Zika virus.
Giraldo MI, Xia H, Aguilera-Aguirre L, Hage A, van Tol S, Shan C, Xie X, Sturdevant GL, Robertson SJ, McNally KL, Meade-White K, Azar SR, Rossi SL, Maury W, Woodson M, Ramage H, Johnson JR, Krogan NJ, Morais MC, Best SM, Shi PY, Rajsbaum R. Giraldo MI, et al. Among authors: aguilera aguirre l. Nature. 2020 Sep;585(7825):414-419. doi: 10.1038/s41586-020-2457-8. Epub 2020 Jul 8. Nature. 2020. PMID: 32641828 Free PMC article.
The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity.
Hage A, Bharaj P, van Tol S, Giraldo MI, Gonzalez-Orozco M, Valerdi KM, Warren AN, Aguilera-Aguirre L, Xie X, Widen SG, Moulton HM, Lee B, Johnson JR, Krogan NJ, García-Sastre A, Shi PY, Freiberg AN, Rajsbaum R. Hage A, et al. Among authors: aguilera aguirre l. Cell Rep. 2022 Mar 8;38(10):110434. doi: 10.1016/j.celrep.2022.110434. Cell Rep. 2022. PMID: 35263596 Free PMC article.
Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly.
van Tol S, Kalveram B, Ilinykh PA, Ronk A, Huang K, Aguilera-Aguirre L, Bharaj P, Hage A, Atkins C, Giraldo MI, Wakamiya M, Gonzalez-Orozco M, Warren AN, Bukreyev A, Freiberg AN, Rajsbaum R. van Tol S, et al. Among authors: aguilera aguirre l. PLoS Pathog. 2022 May 9;18(5):e1010532. doi: 10.1371/journal.ppat.1010532. eCollection 2022 May. PLoS Pathog. 2022. PMID: 35533195 Free PMC article.
Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes.
Aguilera-Aguirre L, Hosoki K, Bacsi A, Radák Z, Wood TG, Widen SG, Sur S, Ameredes BT, Saavedra-Molina A, Brasier AR, Ba X, Boldogh I. Aguilera-Aguirre L, et al. Free Radic Biol Med. 2015 Apr;81:107-18. doi: 10.1016/j.freeradbiomed.2015.01.004. Epub 2015 Jan 19. Free Radic Biol Med. 2015. PMID: 25614460 Free PMC article.
Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation.
Chakraborty A, Wakamiya M, Venkova-Canova T, Pandita RK, Aguilera-Aguirre L, Sarker AH, Singh DK, Hosoki K, Wood TG, Sharma G, Cardenas V, Sarkar PS, Sur S, Pandita TK, Boldogh I, Hazra TK. Chakraborty A, et al. J Biol Chem. 2015 Oct 9;290(41):24636-48. doi: 10.1074/jbc.M115.658146. Epub 2015 Aug 5. J Biol Chem. 2015. PMID: 26245904 Free PMC article.
41 results