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Novel 3,5-bis(arylidene)-4-oxo-1-piperidinyl dimers: structure-activity relationships and potent antileukemic and antilymphoma cytotoxicity.
Santiago-Vazquez Y, Das S, Das U, Robles-Escajeda E, Ortega NM, Lema C, Varela-Ramírez A, Aguilera RJ, Balzarini J, De Clercq E, Dimmock SG, Gorecki DK, Dimmock JR. Santiago-Vazquez Y, et al. Among authors: aguilera rj. Eur J Med Chem. 2014 Apr 22;77:315-22. doi: 10.1016/j.ejmech.2014.03.009. Epub 2014 Mar 6. Eur J Med Chem. 2014. PMID: 24657568 Free PMC article.
The gender of cell lines matters when screening for novel anti-cancer drugs.
Nunes LM, Robles-Escajeda E, Santiago-Vazquez Y, Ortega NM, Lema C, Muro A, Almodovar G, Das U, Das S, Dimmock JR, Aguilera RJ, Varela-Ramirez A. Nunes LM, et al. Among authors: aguilera rj. AAPS J. 2014 Jul;16(4):872-4. doi: 10.1208/s12248-014-9617-4. Epub 2014 May 30. AAPS J. 2014. PMID: 24875051 Free PMC article.
An acylhydroquinone derivative produces OXPHOS uncoupling and sensitization to BH3 mimetic ABT-199 (Venetoclax) in human promyelocytic leukemia cells.
Donoso-Bustamante V, Borrego EA, Schiaffino-Bustamante Y, Gutiérrez DA, Millas-Vargas JP, Fuentes-Retamal S, Correa P, Carrillo I, Aguilera RJ, Miranda D, Chávez-Báez I, Pulgar R, Urra FA, Varela-Ramírez A, Araya-Maturana R. Donoso-Bustamante V, et al. Among authors: aguilera rj. Bioorg Chem. 2020 Jul;100:103935. doi: 10.1016/j.bioorg.2020.103935. Epub 2020 May 18. Bioorg Chem. 2020. PMID: 32454391
94 results