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Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity.
Aguilera E, Varela J, Birriel E, Serna E, Torres S, Yaluff G, de Bilbao NV, Aguirre-López B, Cabrera N, Díaz Mazariegos S, de Gómez-Puyou MT, Gómez-Puyou A, Pérez-Montfort R, Minini L, Merlino A, Cerecetto H, González M, Alvarez G. Aguilera E, et al. ChemMedChem. 2016 Jun 20;11(12):1328-38. doi: 10.1002/cmdc.201500385. Epub 2015 Oct 23. ChemMedChem. 2016. PMID: 26492824
Multi-Anti-Parasitic Activity of Arylidene Ketones and Thiazolidene Hydrazines against Trypanosoma cruzi and Leishmania spp.
Álvarez G, Perdomo C, Coronel C, Aguilera E, Varela J, Aparicio G, Zolessi FR, Cabrera N, Vega C, Rolón M, Rojas de Arias A, Pérez-Montfort R, Cerecetto H, González M. Álvarez G, et al. Among authors: aguilera e. Molecules. 2017 May 7;22(5):709. doi: 10.3390/molecules22050709. Molecules. 2017. PMID: 28481276 Free PMC article.
Polypharmacology in the Treatment of Chagas Disease.
Aguilera E, Alvarez G, Cerecetto H, González M. Aguilera E, et al. Curr Med Chem. 2019;26(23):4476-4489. doi: 10.2174/0929867325666180410101728. Curr Med Chem. 2019. PMID: 29637852 Review.
Novel and Selective Rhipicephalus microplus Triosephosphate Isomerase Inhibitors with Acaricidal Activity.
Saramago L, Gomes H, Aguilera E, Cerecetto H, González M, Cabrera M, Alzugaray MF, da Silva Vaz Junior I, Nunes da Fonseca R, Aguirre-López B, Cabrera N, Pérez-Montfort R, Merlino A, Moraes J, Álvarez G. Saramago L, et al. Among authors: aguilera e. Vet Sci. 2018 Aug 23;5(3):74. doi: 10.3390/vetsci5030074. Vet Sci. 2018. PMID: 30142944 Free PMC article.
A Nature-Inspired Design Yields a New Class of Steroids Against Trypanosomatids.
Aguilera E, Perdomo C, Espindola A, Corvo I, Faral-Tello P, Robello C, Serna E, Benítez F, Riveros R, Torres S, Vera de Bilbao NI, Yaluff G, Alvarez G. Aguilera E, et al. Molecules. 2019 Oct 22;24(20):3800. doi: 10.3390/molecules24203800. Molecules. 2019. PMID: 31652542 Free PMC article.
Antiprotozoal Compounds from Urolepis hecatantha (Asteraceae).
Elso OG, Clavin M, Hernandez N, Sgarlata T, Bach H, Catalan CAN, Aguilera E, Alvarez G, Sülsen VP. Elso OG, et al. Among authors: aguilera e. Evid Based Complement Alternat Med. 2021 Feb 11;2021:6622894. doi: 10.1155/2021/6622894. eCollection 2021. Evid Based Complement Alternat Med. 2021. PMID: 33628303 Free PMC article.
Preclinical Studies in Anti-Trypanosomatidae Drug Development.
Perdomo C, Aguilera E, Corvo I, Faral-Tello P, Serna E, Robello C, Wilkinson SR, Yaluff G, Alvarez G. Perdomo C, et al. Among authors: aguilera e. Pharmaceuticals (Basel). 2021 Jul 5;14(7):644. doi: 10.3390/ph14070644. Pharmaceuticals (Basel). 2021. PMID: 34358070 Free PMC article.
186 results