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New trifluoromethyl triazolopyrimidines as anti-Plasmodium falciparum agents.
Boechat N, Pinheiro LC, Silva TS, Aguiar AC, Carvalho AS, Bastos MM, Costa CC, Pinheiro S, Pinto AC, Mendonça JS, Dutra KD, Valverde AL, Santos-Filho OA, Ceravolo IP, Krettli AU. Boechat N, et al. Among authors: aguiar ac. Molecules. 2012 Jul 10;17(7):8285-302. doi: 10.3390/molecules17078285. Molecules. 2012. PMID: 22781441 Free PMC article.
New hybrid trifluoromethylquinolines as antiplasmodium agents.
da Silva RMRJ, Gandi MO, Mendonça JS, Carvalho AS, Coutinho JP, Aguiar ACC, Krettli AU, Boechat N. da Silva RMRJ, et al. Bioorg Med Chem. 2019 Mar 15;27(6):1002-1008. doi: 10.1016/j.bmc.2019.01.044. Epub 2019 Feb 2. Bioorg Med Chem. 2019. PMID: 30737133 Free article.
Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors.
Silveira FF, de Souza JO, Hoelz LVB, Campos VR, Jabor VAP, Aguiar ACC, Nonato MC, Albuquerque MG, Guido RVC, Boechat N, Pinheiro LCS. Silveira FF, et al. Eur J Med Chem. 2021 Jan 1;209:112941. doi: 10.1016/j.ejmech.2020.112941. Epub 2020 Oct 21. Eur J Med Chem. 2021. PMID: 33158577
Discovery of new piperaquine hybrid analogs linked by triazolopyrimidine and pyrazolopyrimidine scaffolds with antiplasmodial and transmission blocking activities.
Feitosa LM, Franca RRF, Ferreira MLG, Aguiar ACC, de Souza GE, Maluf SEC, de Souza JO, Zapata L, Duarte D, Morais I, Nogueira F, Nonato MC, Pinheiro LCS, Guido RVC, Boechat N. Feitosa LM, et al. Among authors: aguiar acc. Eur J Med Chem. 2024 Mar 5;267:116163. doi: 10.1016/j.ejmech.2024.116163. Epub 2024 Jan 25. Eur J Med Chem. 2024. PMID: 38290351
Isolation, Derivative Synthesis, and Structure-Activity Relationships of Antiparasitic Bromopyrrole Alkaloids from the Marine Sponge Tedania brasiliensis.
Parra LLL, Bertonha AF, Severo IRM, Aguiar ACC, de Souza GE, Oliva G, Guido RVC, Grazzia N, Costa TR, Miguel DC, Gadelha FR, Ferreira AG, Hajdu E, Romo D, Berlinck RGS. Parra LLL, et al. J Nat Prod. 2018 Jan 26;81(1):188-202. doi: 10.1021/acs.jnatprod.7b00876. Epub 2018 Jan 3. J Nat Prod. 2018. PMID: 29297684 Free PMC article.
104 results