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Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders.
Hatoum AS, Colbert SMC, Johnson EC, Huggett SB, Deak JD, Pathak G, Jennings MV, Paul SE, Karcher NR, Hansen I, Baranger DAA, Edwards A, Grotzinger A; Substance Use Disorder Working Group of the Psychiatric Genomics Consortium; Tucker-Drob EM, Kranzler HR, Davis LK, Sanchez-Roige S, Polimanti R, Gelernter J, Edenberg HJ, Bogdan R, Agrawal A. Hatoum AS, et al. Among authors: agrawal a. Nat Ment Health. 2023 Mar;1(3):210-223. doi: 10.1038/s44220-023-00034-y. Epub 2023 Mar 22. Nat Ment Health. 2023. PMID: 37250466 Free PMC article.
Association of the kappa-opioid system with alcohol dependence.
Xuei X, Dick D, Flury-Wetherill L, Tian HJ, Agrawal A, Bierut L, Goate A, Bucholz K, Schuckit M, Nurnberger J Jr, Tischfield J, Kuperman S, Porjesz B, Begleiter H, Foroud T, Edenberg HJ. Xuei X, et al. Among authors: agrawal a. Mol Psychiatry. 2006 Nov;11(11):1016-24. doi: 10.1038/sj.mp.4001882. Epub 2006 Aug 22. Mol Psychiatry. 2006. PMID: 16924269
Genome-wide association study of conduct disorder symptomatology.
Dick DM, Aliev F, Krueger RF, Edwards A, Agrawal A, Lynskey M, Lin P, Schuckit M, Hesselbrock V, Nurnberger J Jr, Almasy L, Porjesz B, Edenberg HJ, Bucholz K, Kramer J, Kuperman S, Bierut L. Dick DM, et al. Among authors: agrawal a. Mol Psychiatry. 2011 Aug;16(8):800-8. doi: 10.1038/mp.2010.73. Epub 2010 Jun 29. Mol Psychiatry. 2011. PMID: 20585324 Free PMC article.
A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.
Wang JC, Foroud T, Hinrichs AL, Le NX, Bertelsen S, Budde JP, Harari O, Koller DL, Wetherill L, Agrawal A, Almasy L, Brooks AI, Bucholz K, Dick D, Hesselbrock V, Johnson EO, Kang S, Kapoor M, Kramer J, Kuperman S, Madden PA, Manz N, Martin NG, McClintick JN, Montgomery GW, Nurnberger JI Jr, Rangaswamy M, Rice J, Schuckit M, Tischfield JA, Whitfield JB, Xuei X, Porjesz B, Heath AC, Edenberg HJ, Bierut LJ, Goate AM. Wang JC, et al. Among authors: agrawal a. Mol Psychiatry. 2013 Nov;18(11):1218-24. doi: 10.1038/mp.2012.143. Epub 2012 Oct 23. Mol Psychiatry. 2013. PMID: 23089632 Free PMC article.
Evidence of CNIH3 involvement in opioid dependence.
Nelson EC, Agrawal A, Heath AC, Bogdan R, Sherva R, Zhang B, Al-Hasani R, Bruchas MR, Chou YL, Demers CH, Carey CE, Conley ED, Fakira AK, Farrer LA, Goate A, Gordon S, Henders AK, Hesselbrock V, Kapoor M, Lynskey MT, Madden PA, Moron JA, Rice JP, Saccone NL, Schwab SG, Shand FL, Todorov AA, Wallace L, Wang T, Wray NR, Zhou X, Degenhardt L, Martin NG, Hariri AR, Kranzler HR, Gelernter J, Bierut LJ, Clark DJ, Montgomery GW. Nelson EC, et al. Among authors: agrawal a. Mol Psychiatry. 2016 May;21(5):608-14. doi: 10.1038/mp.2015.102. Epub 2015 Aug 4. Mol Psychiatry. 2016. PMID: 26239289 Free PMC article.
Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures.
Kapoor M, Chou YL, Edenberg HJ, Foroud T, Martin NG, Madden PA, Wang JC, Bertelsen S, Wetherill L, Brooks A, Chan G, Hesselbrock V, Kuperman S, Medland SE, Montgomery G, Tischfield J, Whitfield JB, Bierut LJ, Heath AC, Bucholz KK, Goate AM, Agrawal A. Kapoor M, et al. Among authors: agrawal a. Transl Psychiatry. 2016 Mar 22;6(3):e761. doi: 10.1038/tp.2016.27. Transl Psychiatry. 2016. PMID: 27003187 Free PMC article.
An endophenotype approach to the genetics of alcohol dependence: a genome wide association study of fast beta EEG in families of African ancestry.
Meyers JL, Zhang J, Wang JC, Su J, Kuo SI, Kapoor M, Wetherill L, Bertelsen S, Lai D, Salvatore JE, Kamarajan C, Chorlian D, Agrawal A, Almasy L, Bauer L, Bucholz KK, Chan G, Hesselbrock V, Koganti L, Kramer J, Kuperman S, Manz N, Pandey A, Seay M, Scott D, Taylor RE, Dick DM, Edenberg HJ, Goate A, Foroud T, Porjesz B. Meyers JL, et al. Among authors: agrawal a. Mol Psychiatry. 2017 Dec;22(12):1767-1775. doi: 10.1038/mp.2016.239. Epub 2017 Jan 10. Mol Psychiatry. 2017. PMID: 28070124 Free PMC article.
Genome-wide association study identifies a novel locus for cannabis dependence.
Agrawal A, Chou YL, Carey CE, Baranger DAA, Zhang B, Sherva R, Wetherill L, Kapoor M, Wang JC, Bertelsen S, Anokhin AP, Hesselbrock V, Kramer J, Lynskey MT, Meyers JL, Nurnberger JI, Rice JP, Tischfield J, Bierut LJ, Degenhardt L, Farrer LA, Gelernter J, Hariri AR, Heath AC, Kranzler HR, Madden PAF, Martin NG, Montgomery GW, Porjesz B, Wang T, Whitfield JB, Edenberg HJ, Foroud T, Goate AM, Bogdan R, Nelson EC. Agrawal A, et al. Mol Psychiatry. 2018 May;23(5):1293-1302. doi: 10.1038/mp.2017.200. Epub 2017 Nov 7. Mol Psychiatry. 2018. PMID: 29112194 Free PMC article.
Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls.
Pettersson E, Lichtenstein P, Larsson H, Song J; Attention Deficit/Hyperactivity Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Autism Spectrum Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Bipolar Disorder Working Group of the PGC, Eating Disorder Working Group of the PGC, Major Depressive Disorder Working Group of the PGC, Obsessive Compulsive Disorders and Tourette Syndrome Working Group of the PGC, Schizophrenia CLOZUK, Substance Use Disorder Working Group of the PGC; Agrawal A, Børglum AD, Bulik CM, Daly MJ, Davis LK, Demontis D, Edenberg HJ, Grove J, Gelernter J, Neale BM, Pardiñas AF, Stahl E, Walters JTR, Walters R, Sullivan PF, Posthuma D, Polderman TJC. Pettersson E, et al. Among authors: agrawal a. Psychol Med. 2019 May;49(7):1166-1173. doi: 10.1017/S0033291718002039. Epub 2018 Sep 17. Psychol Med. 2019. PMID: 30221610 Free PMC article.
4,337 results