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Dissecting molecular mechanisms of resistance to NOTCH1-targeted therapy in T-cell acute lymphoblastic leukemia xenografts.
Agnusdei V, Minuzzo S, Pinazza M, Gasparini A, Pezzè L, Amaro AA, Pasqualini L, Bianco PD, Tognon M, Frasson C, Palumbo P, Ciribilli Y, Pfeffer U, Carella M, Amadori A, Indraccolo S. Agnusdei V, et al. Haematologica. 2020 May;105(5):1317-1328. doi: 10.3324/haematol.2019.217687. Epub 2019 Aug 29. Haematologica. 2020. PMID: 31467126 Free PMC article.
An immediate transcriptional signature associated with response to the histone deacetylase inhibitor Givinostat in T acute lymphoblastic leukemia xenografts.
Pinazza M, Borga C, Agnusdei V, Minuzzo S, Fossati G, Paganin M, Michielotto B, De Paoli A, Basso G, Amadori A, te Kronnie G, Indraccolo S. Pinazza M, et al. Among authors: agnusdei v. Cell Death Dis. 2016 Jan 14;6(1):e2047. doi: 10.1038/cddis.2015.394. Cell Death Dis. 2016. PMID: 26764573 Free PMC article.
AKR1C enzymes sustain therapy resistance in paediatric T-ALL.
Bortolozzi R, Bresolin S, Rampazzo E, Paganin M, Maule F, Mariotto E, Boso D, Minuzzo S, Agnusdei V, Viola G, Te Kronnie G, Cazzaniga G, Basso G, Persano L. Bortolozzi R, et al. Among authors: agnusdei v. Br J Cancer. 2018 Apr;118(7):985-994. doi: 10.1038/s41416-018-0014-0. Epub 2018 Mar 8. Br J Cancer. 2018. PMID: 29515258 Free PMC article.
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