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TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation.
Labiano I, Agirre-Lizaso A, Olaizola P, Echebarria A, Huici-Izagirre M, Olaizola I, Esparza-Baquer A, Sharif O, Hijona E, Milkiewicz P, Milkiewicz M, González-Romero F, Aspichueta P, Monte MJ, Marin JJG, Vucur M, Luedde T, Marzioni M, Mann DA, Bujanda L, Rodrigues PM, Banales JM, Perugorria MJ. Labiano I, et al. Among authors: agirre lizaso a. J Hepatol. 2022 Oct;77(4):991-1004. doi: 10.1016/j.jhep.2022.05.044. Epub 2022 Jun 22. J Hepatol. 2022. PMID: 35750136 Free article.
TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms.
Esparza-Baquer A, Labiano I, Sharif O, Agirre-Lizaso A, Oakley F, Rodrigues PM, Zhuravleva E, O'Rourke CJ, Hijona E, Jimenez-Agüero R, Riaño I, Landa A, La Casta A, Zaki MYW, Munoz-Garrido P, Azkargorta M, Elortza F, Vogel A, Schabbauer G, Aspichueta P, Andersen JB, Knapp S, Mann DA, Bujanda L, Banales JM, Perugorria MJ. Esparza-Baquer A, et al. Among authors: agirre lizaso a. Gut. 2021 Jul;70(7):1345-1361. doi: 10.1136/gutjnl-2019-319227. Epub 2020 Sep 9. Gut. 2021. PMID: 32907830 Free PMC article.
Pathogenesis of Cholangiocarcinoma.
Rodrigues PM, Olaizola P, Paiva NA, Olaizola I, Agirre-Lizaso A, Landa A, Bujanda L, Perugorria MJ, Banales JM. Rodrigues PM, et al. Among authors: agirre lizaso a. Annu Rev Pathol. 2021 Jan 24;16:433-463. doi: 10.1146/annurev-pathol-030220-020455. Epub 2020 Dec 2. Annu Rev Pathol. 2021. PMID: 33264573 Review.
A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans.
Caballero-Camino FJ, Rodrigues PM, Wångsell F, Agirre-Lizaso A, Olaizola P, Izquierdo-Sanchez L, Perugorria MJ, Bujanda L, Angelin B, Straniero S, Wallebäck A, Starke I, Gillberg PG, Strängberg E, Bonn B, Mattsson JP, Madsen MR, Hansen HH, Lindström E, Åkerblad P, Banales JM. Caballero-Camino FJ, et al. Among authors: agirre lizaso a. Hepatology. 2023 Sep 1;78(3):709-726. doi: 10.1097/HEP.0000000000000376. Epub 2023 Apr 1. Hepatology. 2023. PMID: 36999529 Free PMC article.
Inhibition of YTHDF1 by salvianolic acid overcomes gluten-induced intestinal inflammation.
Olazagoitia-Garmendia A, Rojas-Márquez H, Romero MDM, Ruiz P, Agirre-Lizaso A, Chen Y, Perugorria MJ, Herrero L, Serra D, Luo C, Bujanda L, He C, Castellanos-Rubio A. Olazagoitia-Garmendia A, et al. Among authors: agirre lizaso a. Gut. 2023 Oct 31:gutjnl-2023-330459. doi: 10.1136/gutjnl-2023-330459. Online ahead of print. Gut. 2023. PMID: 37907258 Free article. No abstract available.
m6A Methylated Long Noncoding RNA LOC339803 Regulates Intestinal Inflammatory Response.
Olazagoitia-Garmendia A, Rojas-Márquez H, Sebastian-delaCruz M, Agirre-Lizaso A, Ochoa A, Mendoza-Gomez LM, Perugorria MJ, Bujanda L, Madrigal AH, Santin I, Castellanos-Rubio A. Olazagoitia-Garmendia A, et al. Among authors: agirre lizaso a. Adv Sci (Weinh). 2024 Apr;11(13):e2307928. doi: 10.1002/advs.202307928. Epub 2024 Jan 25. Adv Sci (Weinh). 2024. PMID: 38273714 Free PMC article.
Gata2 as a Crucial Regulator of Stem Cells in Adult Hematopoiesis and Acute Myeloid Leukemia.
Menendez-Gonzalez JB, Vukovic M, Abdelfattah A, Saleh L, Almotiri A, Thomas LA, Agirre-Lizaso A, Azevedo A, Menezes AC, Tornillo G, Edkins S, Kong K, Giles P, Anjos-Afonso F, Tonks A, Boyd AS, Kranc KR, Rodrigues NP. Menendez-Gonzalez JB, et al. Among authors: agirre lizaso a. Stem Cell Reports. 2019 Aug 13;13(2):291-306. doi: 10.1016/j.stemcr.2019.07.005. Epub 2019 Aug 1. Stem Cell Reports. 2019. PMID: 31378673 Free PMC article.